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Acne and other dermatologic manifestations of Korean polycystic ovary syndrome patients

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Authors
Suh, Dae Hun; Hong, Jong Soo; Jung, Jae Yoon; Yoon, Mi Young; Choi, Young Min
Issue Date
2010-09
Publisher
WILEY-BLACKWELL PUBLISHING, INC
Citation
JOURNAL OF DERMATOLOGY; Vol.37 ; 17-17
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrinologic
disorder in child-bearing age women and has complex signs and
symptoms. In general, PCOS has three characteristics: hyperandrogenism
(HA), irregular menstruation (IM), polycystic ovary
(PCO). According to these characteristics, PCOS can be divided
into four subtypes. PCOS can cause not only obstetrical complications
such as menstrual irregularity, atypical uterine bleeding,
infertility, gestational hypertension but also non-obstetrical
complications such as type 2 diabetes, metabolic syndrome,
cardiovascular disease. These non-obstetrical complications may
be derived from long term exposure of hyperandrogenism,
insulin-resistance and hyperestrogenemia in PCOS patients.
Moreover, PCOS has dermatological manifestations as hirsutism,
acne, alopecia, mainly caused by hyperandrogenism. We investigated
24 PCOS patients who visited Department of Obstetrics
and Gynecology. Acne-specific questionnaire, physical examination
and blood sampling were performed. The mean age of
participants was 24.4 and mean body mass index was 22.4 kg/
m2. IM/HA/PCO subtype of PCOS was most common and
occupied 70.8%. Acanthosis nigricans was detected in 16.7% of
patients. The mean of modified Ferriman-Gallwey (F-G) score
which scoring degree of hirsutism, was 7.6, quite high. Androgenetic
alopecia and seborrhea were detected in 12.5% and
37.5% of patients, respectively. Acne was observed in all patients
except one. The mean grade of acne according to Cunliffes
grading system was 2.0 in face, 0.6 in chest, 0.8 in back. This is
the first investigation of dermatological manifestation in Korean
PCOS patients and we especially examined the characteristics of
acne lesions.
ISSN
0385-2407
Language
English
URI
https://hdl.handle.net/10371/77759
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College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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