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Transmission of Avian Influenza Virus (H3N2) to Dogs
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Song, Daesub | - |
dc.contributor.author | Kang, Bokyu | - |
dc.contributor.author | Lee, Chulseung | - |
dc.contributor.author | Jung, Kwonil | - |
dc.contributor.author | Ha, Gunwoo | - |
dc.contributor.author | Kang, Dongseok | - |
dc.contributor.author | Park, Seongjun | - |
dc.contributor.author | Park, BongKyun | - |
dc.contributor.author | Oh, Jinsik | - |
dc.date.accessioned | 2009-08-25T07:42:58Z | - |
dc.date.available | 2009-08-25T07:42:58Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Emerg Infect Dis. 2008;14:741-746 | en |
dc.identifier.issn | 1080-6040 | - |
dc.identifier.uri | https://hdl.handle.net/10371/7789 | - |
dc.description.abstract | In South Korea, where avian influenza virus subtypes H3N2, H5N1, H6N1, and H9N2 circulate or have been detected, 3 genetically similar canine infl uenza virus (H3N2) strains of avian origin (A/canine/Korea/01/2007, A/canine/ Korea/02/2007, and A/canine/Korea/03/2007) were isolated from dogs exhibiting severe respiratory disease. To determine whether the novel canine infl uenza virus of avian origin was transmitted among dogs, we experimentally infected beagles with this infl uenza virus (H3N2) isolate. The beagles shed virus through nasal excretion, seroconverted, and became ill with severe necrotizing tracheobronchitis and bronchioalveolitis with accompanying clinical signs (e.g., high fever). Consistent with histologic observation of lung lesions, large amounts of avian infl uenza virus binding receptor (SAα 2,3-gal) were identifi ed in canine tracheal, bronchial, and bronchiolar epithelial cells, which suggests potential for direct transmission of avian infl uenza virus (H3N2) from poultry to dogs. Our data provide evidence that dogs may play a role in interspecies transmission and spread of infl uenza virus. | en |
dc.language.iso | en | - |
dc.publisher | National Center for Infectious Diseases | en |
dc.title | Transmission of Avian Influenza Virus (H3N2) to Dogs | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 송대섭 | - |
dc.contributor.AlternativeAuthor | 강보규 | - |
dc.contributor.AlternativeAuthor | 이철승 | - |
dc.contributor.AlternativeAuthor | 정권일 | - |
dc.contributor.AlternativeAuthor | 하건우 | - |
dc.contributor.AlternativeAuthor | 강동석 | - |
dc.contributor.AlternativeAuthor | 박성준 | - |
dc.contributor.AlternativeAuthor | 박봉균 | - |
dc.contributor.AlternativeAuthor | 오진식 | - |
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