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Role of Surgery in the Treatment of Ovarian Metastases From Colorectal Cancer

Cited 22 time in Web of Science Cited 22 time in Scopus
Authors
Chung, Tae-Sung; Chang, Hee Jin; Jung, Kyung Hae; Park, Sang-Yoon; Choi, Hyo Seong; Jeong, Seung-Yong; Lim, Seok-Byung
Issue Date
2009-12-01
Publisher
WILEY-LISS
Citation
JOURNAL OF SURGICAL ONCOLOGY; Vol.100 7; 570-574
Keywords
metastatic ovarian tumormetastasectomycolorectal cancer
Abstract
Background and Objectives: The role of surgical resection in the treatment of metastatic ovarian tumors originating from colorectal cancer (CRC) remains uncertain. We sought to identify a subgroup of patients who would benefit from Surgical resection. Methods: We analyzed the clinicopathological and follow-up data on 34 patients who underwent surgical resection of metastatic ovarian tumors originating from CRC. Results: Synchronous ovarian metastasis was detected in 27 patients (79.4%) and metachronous metastasis in 7 (20.6%). The histologic type of the primary CRC was adenocarcinoma in 26 patients (76.5%), mucinous carcinoma in 7 (20.6%). and signet ring cell carcinoma in 1 (2.9%). Complete cytoreduction was possible in 11 patients (32.4%). The 3-year overall survival (OS) rate was 25.1%. The median OS time was 19 months (range, 2-64 months) in all patients, and 36 months (range, 10-64 months) in patients who underwent complete cytoreduction. Cox`s proportional hazards analysis showed that unilateral ovarian metastasis (relative risk [RR], 0.405; 95% confidence interval [CI], 0.171-0.959) and metastasis confined to the pelvic cavity (RR, 0.165; 95% CI, 0.031-0.878) were significantly associated with favorable prognosis. Conclusions: Surgical resection may be beneficial in selected patients with ovarian metastasis arising from CRC, when metastasis is limited to the pelvis. J. Surg. Oncol. 2009;100:570-574. (C) 2009 Wiley-Liss, Inc.
ISSN
0022-4790
Language
English
URI
https://hdl.handle.net/10371/77925
DOI
https://doi.org/10.1002/jso.21382
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College of Medicine/School of Medicine (의과대학/대학원)Surgery (외과학전공)Journal Papers (저널논문_외과학전공)
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