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Transferrin induces interleukin-18 expression in chronic myeloid leukemia cell line, K-562

DC Field Value Language
dc.contributor.authorPark, Sunyoung-
dc.contributor.authorKim, Tae Sung-
dc.contributor.authorKim, Cherlhyun-
dc.contributor.authorKim, Seonghan-
dc.contributor.authorPark, Hyunjeong-
dc.contributor.authorCho, Dae-Ho-
dc.contributor.authorBang, Sa Ik-
dc.date.accessioned2012-07-03T00:12:22Z-
dc.date.available2012-07-03T00:12:22Z-
dc.date.issued2009-02-
dc.identifier.citationLEUKEMIA RESEARCH; Vol.33 2; 315-320ko_KR
dc.identifier.issn0145-2126-
dc.identifier.urihttps://hdl.handle.net/10371/78153-
dc.description.abstractTransferrin is an iron carrier protein involved in iron uptake and the regulation of cell growth. Although highly proliferative cells express transferrin and its receptor. little is known about the role of transferrin in the cellular response to cytokine production. The non-iron-bound form of transferrin (apo-transferrin) was administered to human chronic myeloid leukemia cell line, K-562 cells to assess Whether it could induce interleukin-18 (IL-18). Apo-transferrin enhanced IL-18 mRNA and protein and. moreover, IL-18 secretion was increased by treatment with apo-transferrin. In conclusion, apo-transferrin regulates IL-18 expression and we suggest that it is involved in cytokine production. (C) 2008 Elsevier Ltd. All rights reserved.ko_KR
dc.language.isoenko_KR
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDko_KR
dc.subjectTransferrinko_KR
dc.subjectLeukemiako_KR
dc.subjectApo-transferrinko_KR
dc.subjectInterleukin-18 (IL-18)ko_KR
dc.subjectProliferationko_KR
dc.titleTransferrin induces interleukin-18 expression in chronic myeloid leukemia cell line, K-562ko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor박선영-
dc.contributor.AlternativeAuthor김태성-
dc.contributor.AlternativeAuthor김철현-
dc.contributor.AlternativeAuthor김성한-
dc.contributor.AlternativeAuthor방사익-
dc.contributor.AlternativeAuthor박현정-
dc.contributor.AlternativeAuthor조대호-
dc.identifier.doi10.1016/j.leukres.2008.08.001-
dc.citation.journaltitleLEUKEMIA RESEARCH-
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