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Cathepsin G increases MMP expression in normal human fibroblasts through fibronectin fragmentation, and induces the conversion of proMMP-1 to active MMP-1
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Son, Eui Dong | - |
dc.contributor.author | Kim, Hyaekyoung | - |
dc.contributor.author | Chi, Hyunjung | - |
dc.contributor.author | Lee, So Hee | - |
dc.contributor.author | Kim, Sujung | - |
dc.contributor.author | Lee, Sera | - |
dc.contributor.author | Hwang, Jae Sung | - |
dc.contributor.author | Chung, Jin Ho | - |
dc.contributor.author | Closs, B. | - |
dc.contributor.author | Lee, Jin Young | - |
dc.date.accessioned | 2012-07-03T01:44:32Z | - |
dc.date.available | 2012-07-03T01:44:32Z | - |
dc.date.issued | 2009-02 | - |
dc.identifier.citation | JOURNAL OF DERMATOLOGICAL SCIENCE; Vol.53(2); 150-152 | ko_KR |
dc.identifier.issn | 0923-1811 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78179 | - |
dc.description.abstract | Fibronectin (Fn) is a glycoprotein that is found in the plasma
and is a component of the extracellular matrix (ECM). It binds to collagen and fibulin, as well as a class of the cell surface adhesion receptors termed integrins, and has been shown to be involved in various biological activities, including cell attachment, cell migration, and wound healing [1]. Fn is readily degraded into fibronectin fragment (Fn-frs) through the action of many different types of proteases [2] containing cathepsin G [3]. The expression of MMP (matrix metalloproteinase) by Fn-frs (Fn-f29; N-terminal heparin binding fragment, 45 kDa; Fn-f45, collagen binding fragment, and 110 kDa; Fn-f110 cell binding fragment) has been studied in chondrocytes [4–6], however, little is known about the roles of Fn-frs, or cathepsin G-mediated fragmentation of Fn, in aged human skin and normal human fibroblasts (NHFs). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ELSEVIER IRELAND LTD | ko_KR |
dc.subject | Fibronectin | ko_KR |
dc.subject | Extracellular matrix | ko_KR |
dc.subject | Cathepsin G | ko_KR |
dc.subject | Skin aging | ko_KR |
dc.subject | Fibronectin fragments | ko_KR |
dc.title | Cathepsin G increases MMP expression in normal human fibroblasts through fibronectin fragmentation, and induces the conversion of proMMP-1 to active MMP-1 | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 손의동 | - |
dc.contributor.AlternativeAuthor | 김혜경 | - |
dc.contributor.AlternativeAuthor | 지현정 | - |
dc.contributor.AlternativeAuthor | 이소희 | - |
dc.contributor.AlternativeAuthor | 이진영 | - |
dc.contributor.AlternativeAuthor | 김수정 | - |
dc.contributor.AlternativeAuthor | 이세라 | - |
dc.contributor.AlternativeAuthor | 정진호 | - |
dc.contributor.AlternativeAuthor | 황재성 | - |
dc.identifier.doi | 10.1016/j.jdermsci.2008.08.006 | - |
dc.citation.journaltitle | JOURNAL OF DERMATOLOGICAL SCIENCE | - |
dc.description.citedreference | Loeser RF, 2003, J BIOL CHEM, V278, P24577, DOI 10.1074/jbc.M304530200 | - |
dc.description.citedreference | Labat-Robert J, 2002, SEMIN CANCER BIOL, V12, P187, DOI 10.1016/S1044-579X(02)00022-6 | - |
dc.description.citedreference | Stanton H, 2002, BIOCHEM J, V364, P181 | - |
dc.description.citedreference | Homandberg GA, 1998, OSTEOARTHR CARTILAGE, V6, P231 | - |
dc.description.citedreference | XIE DL, 1994, ARCH BIOCHEM BIOPHYS, V311, P205 | - |
dc.description.citedreference | HYNES RO, 1990, FIBRONECTINS | - |
dc.description.citedreference | VARTIO T, 1982, EUR J BIOCHEM, V123, P223 | - |
dc.description.citedreference | FYRAND O, 1981, DERMATOLOGICA, V162, P220 | - |
dc.description.tc | 2 | - |
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