Publications
Detailed Information
Changes of psychiatric parameters and their relationships by oral isotretinoin in acne patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hahm, Bong Jin | - |
dc.contributor.author | Min, Seong Uk | - |
dc.contributor.author | Yoon, Mi Young | - |
dc.contributor.author | Shin, Yong Wook | - |
dc.contributor.author | Jung, Jae Yoon | - |
dc.contributor.author | Suh, Dae Hun | - |
dc.contributor.author | Kim, Jin Sook | - |
dc.date.accessioned | 2012-07-03T04:26:03Z | - |
dc.date.available | 2012-07-03T04:26:03Z | - |
dc.date.issued | 2009-05 | - |
dc.identifier.citation | JOURNAL OF DERMATOLOGY; Vol.36(5); 255-261 | ko_KR |
dc.identifier.issn | 0385-2407 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78210 | - |
dc.description.abstract | Oral isotretinoin is a highly effective agent for the treatment of moderate to severe acne, but ever since oral isotretinoin was introduced as a modality for acne, the relationship between oral isotretinoin therapy and psychiatric problems, especially depression, has been controversial. The purposes of this study were to know the acute effects of oral isotretinoin therapy on psychiatric symptoms and to investigate the relationships among them, which have not been reported in the published work. This cohort study included 38 acne patients who started oral isotretinoin therapy. Individual patients were examined before administering oral isotretinoin and 2 and 8 weeks after commencement. Acne severity was graded using the Leeds revised acne grading system. Acute psychiatric effects of oral isotretinoin were assessed using a questionnaire authorized by two psychiatrists. This questionnaire included assessments of acne-related quality of life (Assessment of the Psychological and Social Effects of Acne [APSEA]), depression (Beck`s depression inventory [BDI]), anxiety (Beck`s anxiety inventory [BAI]) and psychopathology (Symptomchecklist-90-revised [SCL-90-R]). Acne grading and APSEA showed similar change patterns. Both improved after 8 weeks of oral isotretinoin treatment. On the other hand, the severity of depression decreased after 2 weeks of treatment. A significant correlation was found between BDI and APSEA, but no correlation was found between BDI and acne grade. These results indicate that oral isotretinoin therapy alleviates depressive symptoms. Improvements in depression are directly related to acne-related life quality improvements rather than to improvement in acne grade. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | WILEY-BLACKWELL PUBLISHING, INC | ko_KR |
dc.subject | acne | ko_KR |
dc.subject | depression | ko_KR |
dc.subject | isotretinoin | ko_KR |
dc.subject | psychiatry | ko_KR |
dc.title | Changes of psychiatric parameters and their relationships by oral isotretinoin in acne patients | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 함봉진 | - |
dc.contributor.AlternativeAuthor | 민성욱 | - |
dc.contributor.AlternativeAuthor | 윤미영 | - |
dc.contributor.AlternativeAuthor | 신용욱 | - |
dc.contributor.AlternativeAuthor | 김진숙 | - |
dc.contributor.AlternativeAuthor | 정재윤 | - |
dc.contributor.AlternativeAuthor | 서대헌 | - |
dc.identifier.doi | 10.1111/j.1346-8138.2009.00635.x | - |
dc.citation.journaltitle | JOURNAL OF DERMATOLOGY | - |
dc.description.citedreference | ANTONIO J, 2007, J EUR ACAD DERMATOL, V21, P556 | - |
dc.description.citedreference | Kaymak Y, 2006, J EUR ACAD DERMATOL, V20, P1256, DOI 10.1111/j.1468-3083.2006.01784.x | - |
dc.description.citedreference | O`Reilly KC, 2006, NEUROPSYCHOPHARMACOL, V31, P1919, DOI 10.1038/sj.npp.1300998 | - |
dc.description.citedreference | Yen JY, 2006, PSYCHIAT CLIN NEUROS, V60, P147 | - |
dc.description.citedreference | Ferguson SA, 2005, TOXICOL SCI, V87, P451, DOI 10.1093/toxsci/kfi262 | - |
dc.description.citedreference | Chia CY, 2005, ARCH DERMATOL, V141, P557 | - |
dc.description.citedreference | Aarstad HJ, 2005, ACTA OTO-LARYNGOL, V125, P557, DOI 10.1080/00016480510027547 | - |
dc.description.citedreference | Sahin M, 2005, NEUROTOX RES, V7, P243 | - |
dc.description.citedreference | Crandall J, 2004, P NATL ACAD SCI USA, V101, P5111, DOI 10.1073/pnas.0306336101 | - |
dc.description.citedreference | Sakai Y, 2004, ANN NY ACAD SCI, V1021, P436, DOI 10.1196/annals.1308.059 | - |
dc.description.citedreference | Wysowski DK, 2001, J AM ACAD DERMATOL, V45, P515 | - |
dc.description.citedreference | Wysowski DK, 2001, NEW ENGL J MED, V344, P460 | - |
dc.description.citedreference | Jick SS, 2000, ARCH DERMATOL, V136, P1231 | - |
dc.description.citedreference | Patton GC, 2000, AUST NZ J PSYCHIAT, V34, P741 | - |
dc.description.citedreference | Layton AM, 2000, J DERMATOL TREAT, V11, P3 | - |
dc.description.citedreference | Kellett SC, 1999, BRIT J DERMATOL, V140, P273 | - |
dc.description.citedreference | MIDDELKOOP T, 1999, J PHARM PRACT, V12, P374 | - |
dc.description.citedreference | O`Brien SC, 1998, J DERMATOL TREAT, V9, P215 | - |
dc.description.citedreference | Gupta MA, 1998, BRIT J DERMATOL, V139, P846 | - |
dc.description.citedreference | Zouboulis CC, 1998, DERMATOLOGY, V196, P21 | - |
dc.description.citedreference | Layton AM, 1997, DERMATOLOGY, V195, P15 | - |
dc.description.citedreference | BYRNE A, 1995, CAN J PSYCHIAT, V40, P567 | - |
dc.description.citedreference | SITZMANN JH, 1995, BRIT J DERMATOL, V133, P241 | - |
dc.description.citedreference | KOO J, 1995, J AM ACAD DERMATOL, V32, pS26 | - |
dc.description.citedreference | RHEE MK, 1995, KOR J PSYCHOPATHOL, V4, P77 | - |
dc.description.citedreference | ALLENBY G, 1993, P NATL ACAD SCI USA, V90, P30 | - |
dc.description.citedreference | HULL SM, 1991, CLIN EXP DERMATOL, V16, P210 | - |
dc.description.citedreference | CRETTAZ M, 1990, BIOCHEM J, V272, P391 | - |
dc.description.citedreference | BECK S, 1990, MANUAL BECK ANXIETY | - |
dc.description.citedreference | HIRSCHELSCHOLZ S, 1989, BRIT J DERMATOL, V120, P639 | - |
dc.description.citedreference | RUBINOW DR, 1987, J AM ACAD DERMATOL, V17, P25 | - |
dc.description.citedreference | DEROGATIS S, 1983, SCL90R CLIN PYCH RES | - |
dc.description.citedreference | HAHN H, 1982, J KOREAN NEUROPSYCHI, V25, P487 | - |
dc.description.citedreference | BECK AT, 1961, ARCH GEN PSYCHIAT, V4, P561 | - |
dc.description.tc | 9 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.