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In vitro Derby Imaging of Cancer Biomarkers Using Quantum Dots
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ko, Mee Hyang | - |
dc.contributor.author | Kim, Soonhag | - |
dc.contributor.author | Kang, Won Jun | - |
dc.contributor.author | Lee, Jung Hwan | - |
dc.contributor.author | Moon, Sung Hwan | - |
dc.contributor.author | Ko, Hae Young | - |
dc.contributor.author | Lee, Dong Soo | - |
dc.contributor.author | Hwang, Do Won | - |
dc.contributor.author | Kang, Hyungu | - |
dc.date.accessioned | 2012-07-03T06:00:24Z | - |
dc.date.available | 2012-07-03T06:00:24Z | - |
dc.date.issued | 2009-05-18 | - |
dc.identifier.citation | SMALL; Vol.5 10; 1207-1212 | ko_KR |
dc.identifier.issn | 1613-6810 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78264 | - |
dc.description.abstract | Semiconductor quantum dots (QDs), which have broad absorption with narrow. emission spectra, are useful for multiplex imaging. Here, fluorescence derby imaging using dual color QDs conjugated by the AS1411 aptamer (targeting nucleolin) and the arginine-glycine-aspartic acid (targeting the integrin alpha(v)beta(3)) in cancer cells is reported. Simultaneous fluorescence imaging of cellular distribution of nucleolin and integrin alpha(v)beta(3) using QDs enables easy monitoring of separate targets in the cancer cells and the normal healthy cells. These results suggest the feasibility of a concurrent visualization of QD-based multiple cancer biomarkers using small molecules such as aptamer or peptide ligands. | ko_KR |
dc.description.sponsorship | This work
was supported by the Nano Bio Regenomics Project of Korean Science and Engineering Foundation, Innovation Cluster for Advanced Medical Imaging Technology, KOSEF MOST (2008- 03767 and M20M04000039-08M0400-03910) and the National R&D Program for Cancer Control of Ministry of Health&Welfare (0820320). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | WILEY-V C H VERLAG GMBH | ko_KR |
dc.subject | derby imaging | ko_KR |
dc.subject | nucleolin aptamers | ko_KR |
dc.subject | quantum dots | ko_KR |
dc.subject | peptides | ko_KR |
dc.title | In vitro Derby Imaging of Cancer Biomarkers Using Quantum Dots | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 고미향 | - |
dc.contributor.AlternativeAuthor | 김순학 | - |
dc.contributor.AlternativeAuthor | 강원준 | - |
dc.contributor.AlternativeAuthor | 이정환 | - |
dc.contributor.AlternativeAuthor | 강현구 | - |
dc.contributor.AlternativeAuthor | 문성환 | - |
dc.contributor.AlternativeAuthor | 황도완 | - |
dc.contributor.AlternativeAuthor | 고해영 | - |
dc.contributor.AlternativeAuthor | 이동수 | - |
dc.identifier.doi | 10.1002/smll.200801580 | - |
dc.citation.journaltitle | SMALL | - |
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dc.description.tc | 22 | - |
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