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개 지방세포 유래의 중간엽 줄기세포의 종양형성시험
Tumorigenesis Study of Canine Adipose Derived-mesenchymal Stem Cell

DC Field Value Language
dc.contributor.author이은선-
dc.contributor.author권은아-
dc.contributor.author박정란-
dc.contributor.author강병철-
dc.contributor.author강경선-
dc.contributor.author조명행-
dc.date.accessioned2008-12-24T07:57:47Z-
dc.date.available2008-12-24T07:57:47Z-
dc.date.issued2007-09-
dc.identifier.citation한국독성학회지en
dc.identifier.urihttps://hdl.handle.net/10371/782-
dc.description.abstractSeveral recent studies demonstrated the potential of bioengineering using stem cells in regenerative medicine. Adult mesenchymal stem cells (MSCs) have the pluripotency to differentiate into cells of mesodermal origin, i.e., bone, cartilage, adipose, and muscle cells; they, therefore, have many potential clinical applications. On the other hand, stem cells possess a self-renewal capability similar to cancer cells. For safety evaluation of MSCs, in this study, we tested tumorigenecity of canine adipose derived mesenchymal stem cells (cAD-MSCs) using Balb/c-nu mice. In this study, there were no changes in mortality, clinical signs, body weights and biochemical parameters of all animals treated. In addition, there were no significant changes between control and treated groups in autopsy findings. These results indicate that cAD-MSC has no tumorigenic potential under the condition in this study.en
dc.language.isootheren
dc.publisher한국독성학회en
dc.subjectCanine adipose derived mesenchymal stem cellsen
dc.subjectBALB/c nu miceen
dc.subjectTumorigenicyen
dc.title개 지방세포 유래의 중간엽 줄기세포의 종양형성시험en
dc.title.alternativeTumorigenesis Study of Canine Adipose Derived-mesenchymal Stem Cellen
dc.typeArticleen
dc.contributor.AlternativeAuthorLee, Eun-sun-
dc.contributor.AlternativeAuthorKwon, Euna-
dc.contributor.AlternativeAuthorPark, Jeong Ran-
dc.contributor.AlternativeAuthorKang, Byung-Chul-
dc.contributor.AlternativeAuthorKang, Kyung-Sun-
dc.contributor.AlternativeAuthorCho, Myung-Haing-
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