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The Effect of Curculigoside on the Expression of Matrix Metalloproteinase-1 in Cultured Human Skin Fibroblasts
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Song-Yi | - |
dc.contributor.author | Kim, Mi-Ran | - |
dc.contributor.author | Choi, Hong Seok | - |
dc.contributor.author | Moon, Hyung-In | - |
dc.contributor.author | Lee, Dong Gun | - |
dc.contributor.author | Woo, Eun-Rhan | - |
dc.contributor.author | Chung, Jin Ho | - |
dc.date.accessioned | 2012-07-04T00:24:40Z | - |
dc.date.available | 2012-07-04T00:24:40Z | - |
dc.date.issued | 2009-10 | - |
dc.identifier.citation | ARCHIVES OF PHARMACAL RESEARCH; Vol.32 10; 1433-1439 | ko_KR |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78336 | - |
dc.description.abstract | The dried rhizomes of Curculigo orchioides G. yielded two phenolic glycosides, curculigoside (1), orcinol-beta-D-glucoside (4), and two cycloartane saponins, curculigosaponin G (2), curculigosaponin I (3). The structures were determined using spectroscopic methods. Among these isolates, compound 1 exhibited potent inhibitory activity against matrix metalloproteinase-1 in cultured human skin fibroblasts. In addition, it increased the level of Bcl-2 protein expression and decreased the level of Bax protein expression. Compound 4 was isolated from this plant for the first time. | ko_KR |
dc.description.sponsorship | This study was supported by a grant from Chosun
University 2009. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | PHARMACEUTICAL SOC KOREA | ko_KR |
dc.subject | Curculigo orchioides G. | ko_KR |
dc.subject | Matrix metalloproteinase-1 | ko_KR |
dc.subject | Type-1 procollagen | ko_KR |
dc.subject | Cycloartane saponin | ko_KR |
dc.subject | Amaryllidaceae | ko_KR |
dc.subject | Phenolic glycoside | ko_KR |
dc.subject | Curculigoside | ko_KR |
dc.title | The Effect of Curculigoside on the Expression of Matrix Metalloproteinase-1 in Cultured Human Skin Fibroblasts | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 이송이 | - |
dc.contributor.AlternativeAuthor | 김미란 | - |
dc.contributor.AlternativeAuthor | 최홍석 | - |
dc.contributor.AlternativeAuthor | 문형인 | - |
dc.contributor.AlternativeAuthor | 정진호 | - |
dc.contributor.AlternativeAuthor | 이동건 | - |
dc.contributor.AlternativeAuthor | 우은란 | - |
dc.identifier.doi | 10.1007/s12272-009-2013-4 | - |
dc.citation.journaltitle | ARCHIVES OF PHARMACAL RESEARCH | - |
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dc.description.tc | 3 | - |
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