Publications
Detailed Information
Biology of melanogenesis and the search for hypopigmenting agents
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Kyoung-Chan | - |
dc.contributor.author | Huh, Sun Young | - |
dc.contributor.author | Choi, Hye Ryung | - |
dc.contributor.author | Kim, Dong-Seok | - |
dc.date.accessioned | 2012-07-04T00:55:17Z | - |
dc.date.available | 2012-07-04T00:55:17Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | DERMATOLOGICA SINICA; Vol.28(2); 53-58 | ko_KR |
dc.identifier.issn | 1027-8117 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78347 | - |
dc.description.abstract | Increased production and accumulation of melanin are characteristics of a large number of skin diseases, including melasma, post-inflammatory hyperpigmentation and lentigo. A number of clinical agents can reduce normal or abnormal pigmentation, but none of these have achieved satisfactory effects. This review discusses the mechanisms behind the different approaches. Tyrosinase is a pivotal enzyme in melanin synthesis. The majority of whitening or lightening agents act by specifically reducing the activity of tyrosinase via several mechanisms: (1) prior to melanin synthesis (interfering with its transcription and/or glycosylation); (2) during melanin synthesis (tyrosinase inhibition, peroxidase inhibition and reduction of byproducts); and (3) after melanin synthesis (tyrosinase degradation, inhibition of melanosome transfer, acceleration of skin turnover). Additional melanogenesis-associated mechanisms are also discussed. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | TAIWANESE DERMATOLOGICAL ASSOC | ko_KR |
dc.subject | Mechanism | ko_KR |
dc.subject | Melanin | ko_KR |
dc.subject | Tyrosinase | ko_KR |
dc.title | Biology of melanogenesis and the search for hypopigmenting agents | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 박경찬 | - |
dc.contributor.AlternativeAuthor | 허선영 | - |
dc.contributor.AlternativeAuthor | 최혜령 | - |
dc.contributor.AlternativeAuthor | 김동석 | - |
dc.citation.journaltitle | DERMATOLOGICA SINICA | - |
dc.description.citedreference | Park SH, 2009, EXP DERMATOL, V18, P562, DOI 10.1111/j.1600-0625.2009.00847.x | - |
dc.description.citedreference | Park SH, 2008, PHARMAZIE, V63, P290, DOI 10.1691/ph.2008.7754 | - |
dc.description.citedreference | Kim DS, 2006, PIGM CELL RES, V19, P146, DOI 10.1111/j.1600-0749.2005.00287.x | - |
dc.description.citedreference | Ando H, 2006, BIOCHEM J, V394, P43, DOI 10.1042/BJ20051419 | - |
dc.description.citedreference | Kim DS, 2005, BIOL PHARM BULL, V28, P2216 | - |
dc.description.citedreference | Ohguchi K, 2005, MOL CELL BIOCHEM, V275, P103, DOI 10.1007/s11010-005-1081-0 | - |
dc.description.citedreference | Park SH, 2004, CELL MOL LIFE SCI, V61, P2878, DOI 10.1007/s00018-004-4341-3 | - |
dc.description.citedreference | Kim DS, 2004, INT J BIOCHEM CELL B, V36, P1482, DOI 10.1016/j.biocel.2003.10.023 | - |
dc.description.citedreference | Yamaguchi Y, 2004, J CELL BIOL, V165, P275, DOI 10.1083/jcb.200311122 | - |
dc.description.citedreference | Ando H, 2004, J BIOL CHEM, V279, P15427, DOI 10.1074/jbc.M313701200 | - |
dc.description.citedreference | Kim DS, 2004, CHEM PHYS LIPIDS, V127, P199, DOI 10.1016/j.chemphyslip.2003.11.002 | - |
dc.description.citedreference | Kim DS, 2003, J CELL SCI, V116, P1699 | - |
dc.description.citedreference | Briganti S, 2003, PIGM CELL RES, V16, P101 | - |
dc.description.citedreference | SAEKI Y, 2003, PIGM CELL RES, V16, P593 | - |
dc.description.citedreference | Yamamura T, 2002, ARCH DERMATOL RES, V294, P349, DOI 10.1007/s00403-002-0345-8 | - |
dc.description.citedreference | Kim DS, 2002, CELL SIGNAL, V14, P779 | - |
dc.description.citedreference | Hakozaki T, 2002, BRIT J DERMATOL, V147, P20 | - |
dc.description.citedreference | Gukasyan GS, 2002, BIOCHEMISTRY-MOSCOW+, V67, P277 | - |
dc.description.citedreference | Kasraee B, 2002, DERMATOLOGY, V205, P329, DOI 10.1159/000066439 | - |
dc.description.citedreference | KASRAEE K, 2002, J INVEST DERMATOL, V118, P205 | - |
dc.description.citedreference | Martinez-Esparza M, 2001, INT J BIOCHEM CELL B, V33, P971 | - |
dc.description.citedreference | Moon KY, 2001, ARCH PHARM RES, V24, P307 | - |
dc.description.citedreference | Minwalla L, 2001, PIGM CELL RES, V14, P185 | - |
dc.description.citedreference | Nishiyama T, 2001, BIOSCI BIOTECH BIOCH, V65, P1127, DOI 10.1271/bbb.65.1127 | - |
dc.description.citedreference | Kim DS, 2001, PIGM CELL RES, V14, P110 | - |
dc.description.citedreference | Seiberg M, 2000, J INVEST DERMATOL, V115, P162 | - |
dc.description.citedreference | Franchi J, 2000, PIGM CELL RES, V13, P165 | - |
dc.description.citedreference | Battaini G, 2000, J BIOL INORG CHEM, V5, P262 | - |
dc.description.citedreference | Fenoll LG, 2000, BIOL CHEM, V381, P313 | - |
dc.description.citedreference | Branza-Nichita N, 2000, J BIOL CHEM, V275, P8169 | - |
dc.description.citedreference | Seiberg M, 2000, EXP CELL RES, V254, P25 | - |
dc.description.citedreference | Ichihashi M, 1999, ANTICANCER RES, V19, P3769 | - |
dc.description.citedreference | Ando H, 1999, J LIPID RES, V40, P1312 | - |
dc.description.citedreference | Saliou C, 1999, FREE RADICAL BIO MED, V26, P174 | - |
dc.description.citedreference | Yokota T, 1998, PIGM CELL RES, V11, P355 | - |
dc.description.citedreference | Chakraborty AK, 1998, PIGM CELL RES, V11, P206 | - |
dc.description.citedreference | Ando H, 1998, ARCH DERMATOL RES, V290, P375 | - |
dc.description.citedreference | Imokawa G, 1997, PIGM CELL RES, V10, P218 | - |
dc.description.citedreference | Yasumoto K, 1997, J BIOL CHEM, V272, P503 | - |
dc.description.citedreference | BOLOGNIA JL, 1995, BRIT J DERMATOL, V133, P349 | - |
dc.description.citedreference | DOOLEY TP, 1994, SKIN PHARMACOL, V7, P188 | - |
dc.description.citedreference | ROS JR, 1993, BIOCHEM J, V295, P309 | - |
dc.description.citedreference | KARG E, 1993, J INVEST DERMATOL, V100, pS209 | - |
dc.description.citedreference | PARK KC, 1993, AM J HUM GENET, V52, P406 | - |
dc.description.citedreference | SUGAI T, 1992, HIFU, V34, P522 | - |
dc.description.citedreference | DISCHIA M, 1991, BIOCHIM BIOPHYS ACTA, V1073, P423 | - |
dc.description.citedreference | MISHIMA Y, 1983, J INVEST DERMATOL, V81, P106 | - |
dc.description.citedreference | KLIGMAN AM, 1975, ARCH DERMATOL, V111, P40 | - |
dc.description.tc | 0 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.