S-Space College of Medicine/School of Medicine (의과대학/대학원) Dermatology (피부과학전공) Journal Papers (저널논문_피부과학전공)
Vitamin D receptor depletion by Wnt/beta-catenin signaling caused alopecia areata in human Immunobiology, Alopecia Areata
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- Issue Date
- WILEY-BLACKWELL PUBLISHING, INC
- EXPERIMENTAL DERMATOLOGY; Vol.19(6); 574-574
- Vitamin D receptor (VDR) is expressed in the epidermal component
of hair follicle and dermal papilla cell and the lack of VDR results alopecia.
In this study, we investigated the VDR expression in the human
normal follicle and the alopecia areata (AA). First, we demonstrated
human tissue was taken for immunohistochemical staing for b-catenin,
Wnt3a, Wnt5a, Wnt10b, proliferating cell nuclear antigen (PCNA),
involucrin and filaggrin.
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