Reduced expression of Vitamin D receptor (VDR) related to alopecia universalis by Wnt/b-catenin signaling pathway Immunobiology, Alopecia Areata

Abstract

Vitamin D receptor (VDR) is expressed in the epidermal component of hair follicle and dermal papilla cell and the lack of VDR results alopecia. Alopecia was divided in various types. (Alopecia areata, Alropecia totalis, alopecia universalis, etc.) Wnt/b-catenin signaling pathway was related to hair growth and structure.