S-Space College of Medicine/School of Medicine (의과대학/대학원) Dermatology (피부과학전공) Journal Papers (저널논문_피부과학전공)
Non-invasive Transdermal Delivery Route Using Electrostatically Interactive Biocompatible Nanocapsules
- Shin, Jinseob; Shin, Kyomin; Lee, Hanna; Nam, Jeong-Beom; Ryu, Jee-Hyun; Suh, Kyung-Do; Shim, Jongwon; Han, Sang-Hoon; Kim, Yeon Kyung; Kim, Jin-Woong; Kang, Byeong Cheol; Lee, Min Jung; Chung, Jin Ho; Char, Kookheon; Kim, Junoh; Kim, Yong-Jin; Han, Joo-Hyun; Jung, Jae-Eun
- Issue Date
- WILEY-V C H VERLAG GMBH
- ADVANCED MATERIALS; Vol.22 6; 739-743
- A robust means of fabricating skin-penetrating and compatible nanocarriers comprising poly(D,L-lactide-co-glycolide) is reported. The resultant nanocapsules have the ability to load biologically active ingredients and selectively release them through the epidermis lipid layer. Their release of genistein (left figure) is determined to be diffusion-control led, and they are shown to successfully deliver molecules, such as nile red (right figure), into biopsied skin samples.
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