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Non-invasive Transdermal Delivery Route Using Electrostatically Interactive Biocompatible Nanocapsules

Cited 13 time in Web of Science Cited 13 time in Scopus
Authors
Shin, Jinseob; Shin, Kyomin; Lee, Hanna; Nam, Jeong-Beom; Ryu, Jee-Hyun; Suh, Kyung-Do; Shim, Jongwon; Han, Sang-Hoon; Kim, Yeon Kyung; Kim, Jin-Woong; Kang, Byeong Cheol; Lee, Min Jung; Chung, Jin Ho; Char, Kookheon; Kim, Junoh; Kim, Yong-Jin; Han, Joo-Hyun; Jung, Jae-Eun
Issue Date
2010-02-09
Publisher
WILEY-V C H VERLAG GMBH
Citation
ADVANCED MATERIALS; Vol.22 6; 739-743
Abstract
A robust means of fabricating skin-penetrating and compatible nanocarriers comprising poly(D,L-lactide-co-glycolide) is reported. The resultant nanocapsules have the ability to load biologically active ingredients and selectively release them through the epidermis lipid layer. Their release of genistein (left figure) is determined to be diffusion-control led, and they are shown to successfully deliver molecules, such as nile red (right figure), into biopsied skin samples.
ISSN
0935-9648
Language
English
URI
http://hdl.handle.net/10371/78367
DOI
https://doi.org/10.1002/adma.200902079
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College of Medicine/School of Medicine (의과대학/대학원)Dermatology (피부과학전공)Journal Papers (저널논문_피부과학전공)
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