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A study of the efficacy of cleansers for acne vulgaris

Cited 16 time in Web of Science Cited 17 time in Scopus
Authors
Choi, Yu Sung; Suh, Ho Seok; Yoon, Mi Young; Min, Seong Uk; Jung, Jae Yoon; Suh, Dae Hun; Lee, Dong Hun; Kim, Jin Sook
Issue Date
2010-05
Publisher
INFORMA HEALTHCARE
Citation
JOURNAL OF DERMATOLOGICAL TREATMENT; Vol.21(3); 201-205
Keywords
acneacne treatmentcleanser
Abstract
Background: Acne treatments are sometimes expensive, and mild acne patients need some simpler form of treatment and, thus, the need for easier and cheaper ways of managing acne is increasing.Methods: An 8-week, double-blind, randomized clinical trial was conducted to determine whether cleansers are effective at producing clinical improvements in patients with acne vulgaris. A total of 13 acne patients applied cleanser A to one half of the face and cleanser B (cleanser A plus triclosan, salicylic acid, and azelaic acid) to the other half, twice daily.Results: The numbers of inflammatory and non-inflammatory lesions decreased on both sides. A rebound tendency was noted for cleanser A with respect to inflammatory lesions at 4 weeks post-discontinuation, whereas inflammatory lesions continued to decrease on sides treated with cleanser B during this period. However, non-inflammatory lesion counts were not significantly different in the two groups. Though patients were generally satisfied with both treatments, they were more satisfied with cleanser B. Moreover, histopathologic examinations showed a profound decrease in inflammatory reactions in the cleanser B group.Conclusion: These results show that acne cleansers reduced both inflammatory and non-inflammatory acne lesion counts, and might be helpful for acne treatment.
ISSN
0954-6634
Language
English
URI
http://hdl.handle.net/10371/78371
DOI
https://doi.org/10.3109/09546630903401454
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dermatology (피부과학전공)Journal Papers (저널논문_피부과학전공)
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