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Structural Brain Alterations in Individuals at Ultra-high Risk for Psychosis: A Review of Magnetic Resonance Imaging Studies and Future Directions

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dc.contributor.authorJung, Wi Hoon-
dc.contributor.authorJang, Joon Hwan-
dc.contributor.authorByun, Min Soo-
dc.contributor.authorAn, Suk Kyoon-
dc.contributor.authorKwon, Jun Soo-
dc.date.accessioned2012-07-04T05:34:29Z-
dc.date.available2012-07-04T05:34:29Z-
dc.date.issued2010-12-
dc.identifier.citationJOURNAL OF KOREAN MEDICAL SCIENCE; Vol.25 12; 1700-1709ko_KR
dc.identifier.issn1011-8934-
dc.identifier.urihttps://hdl.handle.net/10371/78413-
dc.description.abstractIndividuals at ultra-high-risk (UHR) for psychosis have become a major focus for research designed to explore markers for early detection of and clinical intervention in schizophrenia. In particular, structural magnetic resonance imaging studies in UHR individuals have provided important insight into the neurobiological basis of psychosis and have shown the brain changes associated with clinical risk factors. In this review, we describe the structural brain abnormalities in magnetic resonance images in UHR individuals. The current accumulated data demonstrate that abnormalities in the prefrontal and temporal cortex and anterior cingulate cortex occur before illness onset. These regions are compatible with the regions of structural deficits found in schizophrenia and first-episode patients. In addition, the burgeoning evidence suggests that such structural abnormalities are potential markers for the transition to psychosis. However, most findings to date are limited because they are from cross-sectional rather than longitudinal studies. Recently, researchers have emphasized neurodevelopmental considerations with respect to brain structural alterations in UHR individuals. Future studies should be conducted to characterize the differences in the brain developmental trajectory between UHR individuals and healthy controls using a longitudinal design. These new studies should contribute to early detection and management as well as provide more predictive markers of later psychosis.ko_KR
dc.language.isoenko_KR
dc.publisherKOREAN ACAD MEDICAL SCIENCESko_KR
dc.subjectSchizophreniako_KR
dc.subjectNeurodevelopmentko_KR
dc.subjectPredictive Markerko_KR
dc.subjectPsychotic Disordersko_KR
dc.subjectUltra-high-riskko_KR
dc.subjectMagnetic Resonance Imagingko_KR
dc.titleStructural Brain Alterations in Individuals at Ultra-high Risk for Psychosis: A Review of Magnetic Resonance Imaging Studies and Future Directionsko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor정이훈-
dc.contributor.AlternativeAuthor장준환-
dc.contributor.AlternativeAuthor변민수-
dc.contributor.AlternativeAuthor안석균-
dc.contributor.AlternativeAuthor권준수-
dc.identifier.doi10.3346/jkms.2010.25.12.1700-
dc.citation.journaltitleJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.description.citedreferenceJung WH, 2011, SCHIZOPHRENIA BULL, V37, P839, DOI 10.1093/schbul/sbp151-
dc.description.citedreferenceWinkler AM, 2010, NEUROIMAGE, V53, P1135, DOI 10.1016/j.neuroimage.2009.12.028-
dc.description.citedreferenceShim G, 2010, BEHAV BRAIN FUNCT, V6, DOI 10.1186/1744-9081-6-58-
dc.description.citedreferenceWood SJ, 2010, NEUROIMAGE, V52, P62, DOI 10.1016/j.neuroimage.2010.04.012-
dc.description.citedreferenceSmieskova R, 2010, NEUROSCI BIOBEHAV R, V34, P1207, DOI 10.1016/j.neubiorev.2010.01.016-
dc.description.citedreferenceBuehlmann E, 2010, J PSYCHIATR RES, V44, P447, DOI 10.1016/j.jpsychires.2009.10.008-
dc.description.citedreferenceKim HS, 2010, SCHIZOPHR RES, V118, P81, DOI 10.1016/j.schres.2010.01.003-
dc.description.citedreferenceTakahashi T, 2010, BRIT J PSYCHIAT, V196, P206, DOI 10.1192/bjp.bp.109.069732-
dc.description.citedreferenceWitthaus H, 2010, J PSYCHIATR NEUROSCI, V35, P33, DOI 10.1503/jpn.090013-
dc.description.citedreferenceByun MS, 2009, PSYCHIAT INVEST, V6, P264, DOI 10.4306/pi.2009.6.4.264-
dc.description.citedreferenceWitthaus H, 2009, PSYCHIAT RES-NEUROIM, V173, P163, DOI 10.1016/j.pscychresns.2008.08.002-
dc.description.citedreferenceStone JM, 2009, BIOL PSYCHIAT, V66, P533, DOI 10.1016/j.biopsych.2009.05.006-
dc.description.citedreferenceKoutsouleris N, 2009, BRIT J PSYCHIAT, V195, P218, DOI 10.1192/bjp.bp.108.052068-
dc.description.citedreferencePantelis C, 2009, NEUROPSYCHOL REV, V19, P385, DOI 10.1007/s11065-009-9114-1-
dc.description.citedreferenceKoutsouleris N, 2009, ARCH GEN PSYCHIAT, V66, P700-
dc.description.citedreferenceShin KS, 2009, BIOL PSYCHIAT, V65, P1071, DOI 10.1016/j.biopsych.2008.12.024-
dc.description.citedreferenceSun JH, 2009, BRAIN RES REV, V61, P14, DOI 10.1016/j.brainresrev.2009.03.004-
dc.description.citedreferenceNelson B, 2009, NEUROSCI BIOBEHAV R, V33, P807, DOI 10.1016/j.neubiorev.2009.01.002-
dc.description.citedreferenceTakahashi T, 2009, SCHIZOPHR RES, V111, P94, DOI 10.1016/j.schres.2009.03.024-
dc.description.citedreferenceTakahashi T, 2009, ARCH GEN PSYCHIAT, V66, P366-
dc.description.citedreferenceFornito A, 2009, SCHIZOPHR RES, V108, P104, DOI 10.1016/j.schres.2008.12.011-
dc.description.citedreferenceSun D, 2009, SCHIZOPHR RES, V108, P85, DOI 10.1016/j.schres.2008.11.026-
dc.description.citedreferenceHaller S, 2009, RADIOLOGY, V250, P212, DOI 10.1148/radiol.2501072153-
dc.description.citedreferenceBorgwardt SJ, 2008, SCHIZOPHR RES, V106, P108, DOI 10.1016/j.schres.2008.08.007-
dc.description.citedreferenceFornito A, 2008, BIOL PSYCHIAT, V64, P758, DOI 10.1016/j.biopsych.2008.05.032-
dc.description.citedreferenceTakahashi T, 2008, PSYCHIAT RES-NEUROIM, V164, P90, DOI 10.1016/j.pscychresns.2008.03.001-
dc.description.citedreferenceTakahashi T, 2008, SCHIZOPHR RES, V105, P236, DOI 10.1016/j.schres.2008.06.021-
dc.description.citedreferenceMeisenzahl EM, 2008, SCHIZOPHR RES, V104, P44, DOI 10.1016/j.schres.2008.06.023-
dc.description.citedreferenceChoi JS, 2008, PROG NEURO-PSYCHOPH, V32, P1326, DOI 10.1016/j.pnpbp.2008.04.011-
dc.description.citedreferenceMeisenzahl EM, 2008, SCHIZOPHR RES, V102, P150, DOI 10.1016/j.schres.2008.02.023-
dc.description.citedreferenceHurlemann R, 2008, PSYCHOL MED, V38, P843, DOI 10.1017/S0033291708003279-
dc.description.citedreferenceShin YW, 2008, SCHIZOPHRENIA BULL, V34, P538, DOI 10.1093/schbul/sbm118-
dc.description.citedreferenceWood SJ, 2008, SCHIZOPHRENIA BULL, V34, P322, DOI 10.1093/schbul/sbm149-
dc.description.citedreferenceChung YS, 2008, SCHIZOPHR RES, V99, P111, DOI 10.1016/j.schres.2007.11.012-
dc.description.citedreferenceBuckner RL, 2008, ANN NY ACAD SCI, V1124, P1, DOI 10.1196/annals.1440.011-
dc.description.citedreferenceShim G, 2008, AUST NZ J PSYCHIAT, V42, P678-
dc.description.citedreferenceThompson KN, 2007, J PSYCHIATR RES, V41, P561, DOI 10.1016/j.jpsychires.2006.05.010-
dc.description.citedreferenceBorgwardt SJ, 2007, BIOL PSYCHIAT, V61, P1148, DOI 10.1016/j.biopsych.2006.08.009-
dc.description.citedreferenceSalisbury DF, 2007, ARCH GEN PSYCHIAT, V64, P521-
dc.description.citedreferencePukrop R, 2007, SCHIZOPHR RES, V92, P116, DOI 10.1016/j.schres.2007.01.020-
dc.description.citedreferenceJessen F, 2006, SCHIZOPHR RES, V87, P81, DOI 10.1016/j.schres.2006.06.011-
dc.description.citedreferenceSteen RG, 2006, BRIT J PSYCHIAT, V188, P510-
dc.description.citedreferenceLencz T, 2006, BIOL PSYCHIAT, V59, P863, DOI 10.1016/j.biopsych.2005.09.005-
dc.description.citedreferenceVelakoulis D, 2006, ARCH GEN PSYCHIAT, V63, P139-
dc.description.citedreferenceBorgwardt SJ, 2006, J NEUROL NEUROSUR PS, V77, P229, DOI 10.1136/jnnp.2005.069690-
dc.description.citedreferenceCannon TD, 2005, SCHIZOPHR RES, V79, P35, DOI 10.1016/j.schres.2005.06.014-
dc.description.citedreferenceGarner B, 2005, BIOL PSYCHIAT, V58, P417, DOI 10.1016/j.biopsych.2005.04.018-
dc.description.citedreferenceWood SJ, 2005, SCHIZOPHR RES, V75, P295, DOI 10.1016/j.schres.2004.10.008-
dc.description.citedreferenceBrewer WJ, 2005, AM J PSYCHIAT, V162, P71-
dc.description.citedreferenceSowell ER, 2004, J NEUROSCI, V24, P8223, DOI 10.1523/JNEUROSCI.1798-04.2004-
dc.description.citedreferenceRyan MCM, 2004, PSYCHONEUROENDOCRINO, V29, P1065, DOI 10.1016/j.psyneuen.2003.08.011-
dc.description.citedreferenceSowell ER, 2004, NEUROSCIENTIST, V10, P372, DOI 10.1177/1073858404263960-
dc.description.citedreferenceMacMaster FP, 2004, J PSYCHIAT RES, V38, P231, DOI 10.1016/j.jpsychires.2003.11.001-
dc.description.citedreferenceLaBar KS, 2003, CEREB CORTEX, V13, P1023-
dc.description.citedreferenceWood SJ, 2003, PSYCHOL MED, V33, P1239, DOI 10.1017/S0033291703008067-
dc.description.citedreferenceKasai K, 2003, ARCH GEN PSYCHIAT, V60, P766-
dc.description.citedreferenceYucel M, 2003, BRIT J PSYCHIAT, V182, P518-
dc.description.citedreferencePantelis C, 2003, LANCET, V361, P281-
dc.description.citedreferenceWood SJ, 2003, SCHIZOPHRENIA BULL, V29, P831-
dc.description.citedreferencePhillips LJ, 2002, SCHIZOPHR RES, V58, P145-
dc.description.citedreferenceThompson PM, 2001, P NATL ACAD SCI USA, V98, P11650-
dc.description.citedreferenceShenton ME, 2001, SCHIZOPHR RES, V49, P1-
dc.description.citedreferenceKwon JS, 1999, ARCH GEN PSYCHIAT, V56, P142-
dc.description.citedreferenceHirayasu Y, 1998, AM J PSYCHIAT, V155, P1384-
dc.description.citedreferenceKwon JS, 1998, AM J PSYCHIAT, V155, P509-
dc.description.citedreferenceBENES FM, 1993, SCHIZOPHRENIA BULL, V19, P537-
dc.description.citedreferenceSHENTON ME, 1992, NEW ENGL J MED, V327, P604-
dc.description.citedreferenceLIDDLE PF, 1992, BRIT J PSYCHIAT, V160, P179-
dc.description.citedreferenceBARTA PE, 1990, AM J PSYCHIAT, V147, P1457-
dc.description.citedreferenceHAUG H, 1987, AM J ANAT, V180, P126-
dc.description.tc2-
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