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Changes in heart rate dynamics of patients with schizophrenia treated with risperidone

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dc.contributor.authorChang, Jae Seung-
dc.contributor.authorYoo, Cheol Sung-
dc.contributor.authorYi, Sang Hoon-
dc.contributor.authorHong, Kye Hyun-
dc.contributor.authorOh, Hong Seok-
dc.contributor.authorKim, Yong Sik-
dc.contributor.authorAhn, Yong Min-
dc.contributor.authorJung, Dong Chung-
dc.contributor.authorLee, Yu-Sang-
dc.date.accessioned2012-07-04T06:34:39Z-
dc.date.available2012-07-04T06:34:39Z-
dc.date.issued2010-08-16-
dc.identifier.citationPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY; Vol.34 6; 924-929ko_KR
dc.identifier.issn0278-5846-
dc.identifier.urihttps://hdl.handle.net/10371/78437-
dc.description.abstractNeurocardiac dysregulation has been reported in schizophrenia. Indices of heart rate variability (HRV) are useful in assessing the status of cardiac autonomic regulation. We explored within-subject changes in HRV indices in acutely ill patients with schizophrenia treated with risperidone. Sixteen medication-naive or medication-free patients with DSM-IV schizophrenia completed electrocardiogram (ECG) assessments at baseline and after six weeks of treatment with risperidone. Indices of HRV were extracted from 5-min resting ECG recordings and compared to those obtained from control subjects matched for age and gender. Psychiatric and drug-induced extrapyramidal symptoms were assessed by the Positive and Negative Syndrome Scale (PANSS) and the Drug-Induced Extrapyramidal Symptoms Scale (1DIEPSS). In comparison with matched controls, patients with acute schizophrenia showed lower values of time-domain measures, lower high-frequency power (HF) and a higher ratio of low to high frequency (LF/HF). In the within-subject analyses, a significant decrease in LF/HF was associated with risperidone treatment. In addition, LF/HF, which initially co-clustered with clinical variables, congregated with other HRV measures after the six-week risperidone treatment. These results indicate that, in the therapeutic process, risperidone treatment may exert a beneficial influence on the sympathovagal imbalance in acute schizophrenia. (C) 2010 Elsevier Inc. All rights reserved.ko_KR
dc.description.sponsorshipThis study was supported in part by grant A090828 of the Korea
Healthcare Technology R & D project, Ministry of Health, Welfare &
Family Affairs, Republic of Korea, and in part by grant 11-2008-017 from
the Seoul National University Bundang Hospital Research Fund.
ko_KR
dc.language.isoenko_KR
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDko_KR
dc.subjectHeart rate variabilityko_KR
dc.subjectRisperidoneko_KR
dc.subjectSympathovagal balanceko_KR
dc.subjectSchizophreniako_KR
dc.titleChanges in heart rate dynamics of patients with schizophrenia treated with risperidoneko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor장재승-
dc.contributor.AlternativeAuthor유철성-
dc.contributor.AlternativeAuthor이상훈-
dc.contributor.AlternativeAuthor홍계현-
dc.contributor.AlternativeAuthor이유상-
dc.contributor.AlternativeAuthor오홍석-
dc.contributor.AlternativeAuthor정동청-
dc.contributor.AlternativeAuthor김용식-
dc.contributor.AlternativeAuthor안용민-
dc.identifier.doi10.1016/j.pnpbp.2010.04.017-
dc.citation.journaltitlePROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY-
dc.description.citedreferenceHAUTALA K, 2010, AM J PHYSIOL-HEART C, V298, pH874-
dc.description.citedreferenceKim JH, 2009, PSYCHIAT INVEST, V6, P294, DOI 10.4306/pi.2009.6.4.294-
dc.description.citedreferencePeupelmann J, 2009, PROG NEURO-PSYCHOPH, V33, P1236, DOI 10.1016/j.pnpbp.2009.07.007-
dc.description.citedreferenceJindal RD, 2009, SCHIZOPHR RES, V113, P176, DOI 10.1016/j.schres.2009.06.003-
dc.description.citedreferenceChang JS, 2009, PROG NEURO-PSYCHOPH, V33, P991, DOI 10.1016/j.pnpbp.2009.05.004-
dc.description.citedreferenceHempel RJ, 2009, J PSYCHOPHARMACOL, V23, P697, DOI 10.1177/0269881108091254-
dc.description.citedreferencePeupelmann J, 2009, SCHIZOPHR RES, V112, P153, DOI 10.1016/j.schres.2009.03.042-
dc.description.citedreferenceThayer JF, 2009, NEUROSCI BIOBEHAV R, V33, P81, DOI 10.1016/j.neubiorev.2008.08.004-
dc.description.citedreferenceMcNamara RK, 2009, SCHIZOPHR RES, V107, P150, DOI 10.1016/j.schres.2008.09.027-
dc.description.citedreferenceMackowiak M, 2009, EUR NEUROPSYCHOPHARM, V19, P125, DOI 10.1016/j.euroneuro.2008.10.001-
dc.description.citedreferenceRay WA, 2009, NEW ENGL J MED, V360, P225, DOI 10.1056/NEJMoa0806994-
dc.description.citedreferenceChang JS, 2009, AUST NZ J PSYCHIAT, V43, P244, DOI 10.1080/00048670802653299-
dc.description.citedreferenceBAR KJ, 2009, SCHIZOPHR B-
dc.description.citedreferenceBar KB, 2008, J CLIN PSYCHOPHARM, V28, P694, DOI 10.1097/JCP.0b013e31818a6d25-
dc.description.citedreferenceBar KJ, 2008, CLIN NEUROPHYSIOL, V119, P2209, DOI 10.1016/j.clinph.2008.06.012-
dc.description.citedreferenceChang JS, 2008, J CLIN PSYCHIAT, V69, P720-
dc.description.citedreferenceBar KJ, 2008, PSYCHIAT RES, V157, P255, DOI 10.1016/j.psychres.2007.04.021-
dc.description.citedreferenceKoponen H, 2008, NORD J PSYCHIAT, V62, P342, DOI 10.1080/08039480801959323-
dc.description.citedreferenceWang YC, 2008, NEUROPSYCHOBIOLOGY, V57, P200, DOI 10.1159/000149818-
dc.description.citedreferencevon Borell E, 2007, PHYSIOL BEHAV, V92, P293, DOI 10.1016/j.physbeh.2007.01.007-
dc.description.citedreferenceBar KJ, 2007, CLIN NEUROPHYSIOL, V118, P2009, DOI 10.1016/j.clinph.2007.06.012-
dc.description.citedreferenceBar KJ, 2007, SCHIZOPHR RES, V95, P115, DOI 10.1016/j.schres.2007.05.034-
dc.description.citedreferenceBoettger S, 2006, CLIN NEUROPHYSIOL, V117, P2715, DOI 10.1016/j.clinph.2006.08.009-
dc.description.citedreferenceKim JH, 2006, EUR NEUROPSYCHOPHARM, V16, P459, DOI 10.1016/j.euroneuro.2005.11.003-
dc.description.citedreferenceHennekens CH, 2005, AM HEART J, V150, P1115, DOI 10.1016/j.ahj.2005.02.007-
dc.description.citedreferenceJindal R, 2005, J PSYCHIATR NEUROSCI, V30, P393-
dc.description.citedreferenceBar KJ, 2005, J PSYCHIAT RES, V39, P519, DOI 10.1016/j.jpsychires.2004.12.007-
dc.description.citedreferenceMujica-Parodi LR, 2005, NEUROPSYCHOBIOLOGY, V51, P10, DOI 10.1159/000082850-
dc.description.citedreferenceMann K, 2004, INT CLIN PSYCHOPHARM, V19, P325-
dc.description.citedreferenceStraus SMJM, 2004, ARCH INTERN MED, V164, P1293-
dc.description.citedreferenceWilliams LM, 2004, AM J PSYCHIAT, V161, P480-
dc.description.citedreferenceKim JH, 2004, PROG NEURO-PSYCHOPH, V28, P371, DOI 10.1016/j.pnpbp.2003.11.007-
dc.description.citedreferenceValkonen-Korhonen M, 2003, PSYCHOPHYSIOLOGY, V40, P716-
dc.description.citedreferenceAgelink MW, 2003, PHARMACOPSYCHIATRY, V36, P166-
dc.description.citedreferenceSilke B, 2002, J PSYCHOPHARMACOL, V16, P355-
dc.description.citedreferenceMietus JE, 2002, HEART, V88, P378-
dc.description.citedreferenceEschweiler GW, 2002, PHARMACOPSYCHIATRY, V35, P96-
dc.description.citedreferenceYeragani VK, 2002, PSYCHIAT RES, V109, P81-
dc.description.citedreferenceCohen H, 2001, BRIT J PSYCHIAT, V179, P167-
dc.description.citedreferenceAgelink MW, 2001, J CLIN PSYCHOPHARM, V21, P8-
dc.description.citedreferencePorta A, 2000, IEEE T BIO-MED ENG, V47, P1555, DOI 10.1109/10.887936-
dc.description.citedreferenceHuikuri HV, 2000, CIRCULATION, V101, P47-
dc.description.citedreferenceRICHMAN JS, 2000, AM J PHYSIOL-HEART C, V278, P2039-
dc.description.citedreferenceToichi M, 1999, INT J PSYCHOPHYSIOL, V31, P147-
dc.description.citedreferenceMassin MM, 1999, CARDIOLOGY, V91, P109-
dc.description.citedreferenceNolan J, 1998, CIRCULATION, V98, P1510-
dc.description.citedreferenceRechlin T, 1998, PSYCHOPHARMACOLOGY, V135, P338-
dc.description.citedreferencePincus S, 1996, P NATL ACAD SCI USA, V93, P2083-
dc.description.citedreferenceINADA T, 1996, EVALUATION DIAGNOSIS-
dc.description.citedreferenceCOHEN J, 1988, STAT POWER ANAL BEHA-
dc.description.citedreferenceKAY SR, 1987, SCHIZOPHRENIA BULL, V13, P261-
dc.description.citedreferenceALDENDERFER MS, 1984, CLUSTER ANAL-
dc.description.citedreferenceGUY W, 1976, ASSESSMENT MANUAL PS-
dc.description.tc3-
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College of Medicine/School of Medicine (의과대학/대학원)Psychiatry (정신과학전공)Journal Papers (저널논문_정신과학전공)
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