S-Space College of Medicine/School of Medicine (의과대학/대학원) Psychiatry (정신과학전공) Journal Papers (저널논문_정신과학전공)
Quantitative electroencephalographic (qEEG) correlates of craving during virtual reality therapy in alcohol-dependent patients
- Lee, Sang Hoon; Han, Doug Hyun; Oh, Seman; Lyoo, In Iyoon; Renshaw, Perry F.; Lukas, Scott E.; Lee, Young Sik
- Issue Date
- PERGAMON-ELSEVIER SCIENCE LTD
- PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Vol.91(3); 393-397
- Virtual reality (VR) is an evolving technology that is being applied to treat a wide range of medical and psychiatric diseases. A virtual reality therapy (VRT) with multisensory stimulation has been applied to patients with alcohol dependence (ADP). We hypothesized that the VRTP for alcohol dependence would reduce the craving for alcohol and increase alpha wave activity in frontal areas of individuals with ADP. Twenty ADP and eighteen AN were exposed to a series of 10 VRTP sessions (VRTP-ADP) and cognitive behavioral therapy (nVRTP-ADP), respectively. Fifteen healthy controls were exposed to VRTP for comparing the changes of craving and EEG during all three phases of VRTP. The VRTP-ADP exhibited a greater decrease in craving after the 10th VRTP session, when compared to the nVRTP-ADP. Compared to the healthy control subjects, VRTP-ADP group showed higher magnitude of the change in craving throughout VRTP sessions. These results suggest that VRTP may be useful as an adjunct to treating alcohol dependence but may also serve as an evaluation tool to identify high-risk patients.
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