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Polarity of the First Episode and Time to Diagnosis of Bipolar I Disorder
DC Field | Value | Language |
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dc.contributor.author | Cha, Boseok | - |
dc.contributor.author | Kim, Jeong Hyun | - |
dc.contributor.author | Ha, Tae Hyon | - |
dc.contributor.author | Chang, Jae Seung | - |
dc.contributor.author | Ha, Kyooseob | - |
dc.date.accessioned | 2012-07-05T02:30:53Z | - |
dc.date.available | 2012-07-05T02:30:53Z | - |
dc.date.issued | 2009-06 | - |
dc.identifier.citation | PSYCHIATRY INVESTIGATION; Vol.6(2); 96-101 | ko_KR |
dc.identifier.issn | 1738-3684 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78566 | - |
dc.description.abstract | Objective The current study explored the relationship between the polarity of the first episode and the timing of eventual diagnosis of bipolar I disorder, and associated clinical implications. Methods Twelve years of clinical data from the medical records of 258 inpatients meeting DSM-III-R or DSM-IV criteria for bipolar I disorder were analyzed. Subjects were divided into two groups according to the polarity of the first episode: those with depressive polarity (FE-D), and those with manic polarity (FE-M). Comparisons were made between the two groups on variables associated with the timing of diagnosis and related outcomes. Results In Population with bipolar I disorder, a significant longer time lapse from the first major mood episode to the confirmed diagnosis was associated with the FE-D group compared to the FE-M group [5.6 (+/- 6.1) vs. 2.5 (+/- 5.5) years, p<0.001]. FE-D subjects tended to have prior diagnoses of schizophrenia and major depressive disorder while FE-M subjects tended to have prior diagnoses of bipolar disorder and schizophrenia. A significantly higher rate of suicide attempts was associated with the FE-D group compared to the FE-M group (12.7 vs. 1.7%, p<0.001). Conclusion The results of this study indicate that first-episode depressive polarity is likely to be followed by a considerable delay until an eventual confirmed diagnosis of bipolar I disorder. Given that first-episode depressive patients are particularly vulnerable to unfavorable clinical Outcomes Such as suicide attempts, a more systematic approach is needed to differentiate bipolar disorder among depressed patients in their early stages. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KOREAN NEUROPSYCHIATRIC ASSOC | ko_KR |
dc.subject | Bipolar disorder | ko_KR |
dc.subject | Suicide | ko_KR |
dc.subject | Diagnosis | ko_KR |
dc.subject | Polarity | ko_KR |
dc.subject | First episode | ko_KR |
dc.title | Polarity of the First Episode and Time to Diagnosis of Bipolar I Disorder | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 차보석 | - |
dc.contributor.AlternativeAuthor | 김정현 | - |
dc.contributor.AlternativeAuthor | 하태현 | - |
dc.contributor.AlternativeAuthor | 장재승 | - |
dc.contributor.AlternativeAuthor | 하규섭 | - |
dc.identifier.doi | 10.4306/pi.2009.6.2.96 | - |
dc.citation.journaltitle | PSYCHIATRY INVESTIGATION | - |
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dc.description.tc | 1 | - |
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