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Effect of Repetitive Transcranial Magnetic Stimulation Over the Hand Motor Cortical Area on Central Pain After Spinal Cord Injury

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dc.contributor.authorKang, Bo Sung-
dc.contributor.authorShin, Hyung Ik-
dc.contributor.authorBang, Moon Suk-
dc.date.accessioned2012-07-05T04:30:11Z-
dc.date.available2012-07-05T04:30:11Z-
dc.date.issued2009-10-
dc.identifier.citationARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION; Vol.90 10; 1766-1771ko_KR
dc.identifier.issn0003-9993-
dc.identifier.urihttp://hdl.handle.net/10371/78586-
dc.description.abstractObjective: To evaluate the analgesic effect of repetitive transcranial magnetic stimulation (rTMS) applied on the hand motor cortical area in patients with spinal cord injury (SCI) who have chronic neuropathic pain at multiple sites in the body, including the lower limbs, trunk, and pelvis. Design: Blinded, randomized crossover study. Setting: University hospital outpatient setting. Participants: Patients (N = 13) with motor complete or incomplete SCI and chronic central pain (11 completed the study). Interventions: rTMS was applied on the hand motor cortical area using a figure-of-eight coil. One thousand stimuli were applied daily on 5 consecutive days. Real and sham rTMS were separated by 12 weeks. Main Outcome Measures: Numeric rating scale (NRS) for average and worst pain and the Brief Pain Inventory (BPI). Results: At 1 week after the end of the rTMS period, the average NRS scores changed from 6.45 +/- 2.25 to 5.45 +/- 1.81 with real stimulation and from 6.18 +/- 1.83 to 5.91 +/- 2.07 with sham stimulation, and did not differ between treatments. The interference items of the BPI also did not differ between the real and sham rTMS. The effect of time on the NRS score for worst pain was significant with real stimulation but not with sham stimulation. Conclusions: The therapeutic efficacy of rTMS was not demonstrated when rTMS was applied to the hand motor cortical area in patients with chronic neuropathic pain at multiple sites in the body, including the lower limbs, trunk, and pelvis. However, the results for worst pain reduction suggest that further studies are required in which rTMS is applied with a more intensive stimulation protocol.ko_KR
dc.language.isoenko_KR
dc.publisherW B SAUNDERS CO-ELSEVIER INCko_KR
dc.subjectPainko_KR
dc.subjectRehabilitationko_KR
dc.subjectTranscranial magnetic stimulationko_KR
dc.subjectSpinal cord injuriesko_KR
dc.titleEffect of Repetitive Transcranial Magnetic Stimulation Over the Hand Motor Cortical Area on Central Pain After Spinal Cord Injuryko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor강보성-
dc.contributor.AlternativeAuthor신형익-
dc.contributor.AlternativeAuthor방문석-
dc.identifier.doi10.1016/j.apmr.2009.04.008-
dc.citation.journaltitleARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION-
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College of Medicine/School of Medicine (의과대학/대학원)Rehabilitation Medicine (재활의학전공)Journal Papers (저널논문_재활의학전공)
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