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In Vivo Bioluminescent Imaging of Rat Mesenchymal Stem Cells in a Mouse Model of Hindlimb Ischemia

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dc.contributor.authorChung, Hye Kyung-
dc.contributor.authorChung, June-Key-
dc.contributor.authorKang, Joo Hyun-
dc.contributor.authorKim, Seunghoo-
dc.contributor.authorLee, Dong Soo-
dc.contributor.authorKim, Hyun Joo-
dc.date.accessioned2012-07-05T04:34:17Z-
dc.date.available2012-07-05T04:34:17Z-
dc.date.issued2009-06-
dc.identifier.citationTISSUE ENGINEERING AND REGENERATIVE MEDICINE; Vol.6, Issues 4-11; 668-674ko_KR
dc.identifier.issn1738-2696-
dc.identifier.urihttps://hdl.handle.net/10371/78587-
dc.description.abstractWe developed a luciferase gene imaging system Using a retrovirus for monitoring mesenchymal stem cell distribution. Retrovirus expressing firefly luciferase was infected into rat mesenchymal stein cells(rMSCs). rMSC-luc cells were excellent correlations between in vitro and in vivo bioluminescent activities and cell numbers. After systemic injections of cells in mice, luminescence activity was observed until six days, but was not detected in ischemic regions. After local injection with scaffold, luminescence activities were detected in injection sites over 3 weeks. This system Could be a useful means for in vivo real time imaging of stem cell distributions, viability, and trafficking.-
dc.language.isoenko_KR
dc.publisherKOREAN TISSUE ENGINEERING REGENERATIVE MEDICINE SOCko_KR
dc.subjectStem cells-
dc.subjectreporter gene imaging-
dc.subjectfirefly luciferase-
dc.subjecthindlimb ischemia-
dc.titleIn Vivo Bioluminescent Imaging of Rat Mesenchymal Stem Cells in a Mouse Model of Hindlimb Ischemiako_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor정혜경-
dc.contributor.AlternativeAuthor정준기-
dc.contributor.AlternativeAuthor강주현-
dc.contributor.AlternativeAuthor김승후-
dc.contributor.AlternativeAuthor김현주-
dc.contributor.AlternativeAuthor이동수-
dc.citation.journaltitleTISSUE ENGINEERING AND REGENERATIVE MEDICINE-
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dc.description.tc0-
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