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Assessment of Antibiotic Resistance Phenotype and Integrons in Salmonella enterica serovar Typhimurium Isolated from Swine
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Rayamajhi, Nabin | - |
dc.contributor.author | Kang, Sang Gyun | - |
dc.contributor.author | Kang, Mi Lan | - |
dc.contributor.author | Lee, Hee Soo | - |
dc.contributor.author | Park, Kyung Yoon | - |
dc.contributor.author | Yoo, Han Sang | - |
dc.date.accessioned | 2009-08-27 | - |
dc.date.available | 2009-08-27 | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | J. Vet. Med. Sci. 70: 1133-1137 | en |
dc.identifier.issn | 0916-7250 (print) | - |
dc.identifier.issn | 1347-7439 (online) | - |
dc.identifier.uri | https://hdl.handle.net/10371/7906 | - |
dc.description.abstract | Salmonella enterica serovar Typhimurium (S. Typhimurium) isolated and identified from swine were subjected for the analysis
of antibiotic resistance pattern and clinically important class 1 and 2 integrons. In addition, S. Typhimurium isolates exhibiting ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, tetracycline and florfenicol (ACSSuTF) resistance pattern as described in most Salmonella enterica serotype Typhimurium definitive type 104 (DT104) were characterized by polymerase chain reaction. All the isolates were resistant to more than four antibiotics and showed the highest resistance to streptomycin (94.1%), followed by tetracycline (90.1%), ampicillin (64.7%), chloramphenicol (56.8%) and gentamicin (54.9%). MIC value for the ten isolates ranged between 0.125– 2 μg/ml for ciprofloxacin. Among the beta-lactams used, only one of the isolate exhibited resistance to ceftiofur (MIC 8 μg/ml). Sixty eight percent of these multi drug resistance (MDR) S. Typhimurium isolates carried clinically important class 1 integron with 1kb (aadA) and/or 2kb (dhfrXII-orfF-aadA2) resistance gene cassettes. This study reports the increasing trend of multi drug resistance (MDR) S. Typhimurium with clinically important class 1 integron in pigs. In addition, emergence of the ACSSuTF-type resistance in S. Typhimurium PT other than DT104 may limit the use of resistance gene markers in its detection methods by PCR. | en |
dc.description.sponsorship | We are grateful to Prof. Je
Chul Lee and Hyuk Joon Kwon for their enthusiastic support and guidance. This work was supported by the Korea Research Foundation Grant funded by Korea Research Foundation, KRF-2006–005–J02901 and KRF-2006–21– E00011, BK-21 and Bio-Green (20070401–034–009–007– 02–00), RDA, Korea. | en |
dc.language.iso | en | en |
dc.publisher | Japanese Society of Veterinary Science | en |
dc.subject | Integron | en |
dc.subject | PCR | en |
dc.subject | Salmonella Typhimurium | en |
dc.title | Assessment of Antibiotic Resistance Phenotype and Integrons in Salmonella enterica serovar Typhimurium Isolated from Swine | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 강상균 | - |
dc.contributor.AlternativeAuthor | 강미란 | - |
dc.contributor.AlternativeAuthor | 이희수 | - |
dc.contributor.AlternativeAuthor | 박경윤 | - |
dc.contributor.AlternativeAuthor | 유한상 | - |
dc.identifier.doi | 10.1292/jvms.70.1133 | - |
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