난소종양의 병리학적 연구

Abstract

A total of 726 cases of ovarian tumor was obtained from the pathology file of the Department of Pathology, College of Medicine, Seoul National University during a period of 13 years beginning from January 1968 to December 1980. These tumors consisted of 605 cases (83. %) of benign tumors and 121 cases 06.7%) of malignant tumors. Metastatic carcinoma was the most frequent malignant tumor (24.0%), followed by mucinous borderline tumor Cl7.4%), serous carcinoma (9.996), and serous borderline tumor (9.1%). Among germ-cell malignancies dysgerminoma was the most frequent tumor (4.1%), followed by mature cystic teratoma with malignant transformation (3.3 %), endodermal sinus tumor (2.5%). Mature cystic teratoma was the most frequent benign tumor (24.096), followed by serous cystadenoma and adenofibroma (25.1%), mucinous cystadenoma and adenofibroma (22.196), and fibromata. 5%). Benign tumors were most prevalent during the reproductive period, but malignant tumors were prevalent in older age group, particular after the age of 40; malignant tumor of germ cell origin such as dysgerminoma. endodermal sinus tumor, and immature teratoma was prevalent in the 1st and 2nd decade of life. Bilateral involvement was most frequent in metastatic carcinoma (69.2%) followed by serous carcinoma (54.596), cystic teratoma Cl2.8%), and serous cystadenoma ClO.8%). The chief complaints of ovarian tumor patients were abdominal pain, palpable abdominal mass, and menstrual abnormality. Duration of symptoms prior to admission was longer in benign tumor than in malignant tumors. There were very rare tumors, which were not in record in Korean literature. They were 1 case of sclerosing stromal tumor, 1 case of insular carcinoid primary in the ovary, 1 case of juvenlie granulosa cell tumor, and 2 cases of gonadoblastorna with dysgerminoma. Detailed descriptions were given on these rare tumors. In summary germ cell tumors were relatively frequent in Korea than western country. This may be explained by a lower incidence of common epithelial tumor.