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IgA Nephropathy : Ig A 신사구체염

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dc.identifier.citationSeoul J Med, Vol.23 No.4, pp. 424-435-
dc.description.abstractThrough the immunoflurescence study on
368 renal biopsy specimen that were collected
between the year of 1979 and 1981, we found
94 cases of IgA nephropathy without evidence of
systemic diseases, thus showing 27.8% relative
frequency among primary glomerulonephritides
among Koreans. The deposits were IgA alone
in 27.7%, IgA-IgG combination in 42.55'6,
IgA-IgM in 14. 9?6 and IgA-IgG-IgM in 11. 9%.
Early complement C.l deposits were seen in 2
cases. The glomerular morphological patterns were:
minor change with increased mesangial matrix
and cells in 51. 0?6, diffuse mesangial proliferative
glomerulonephritis in 19.290, focal and
segmental proliferative glomerulonephritis in
11. 7?6, and diffuse sclerosing glomerulonephritis
in 9. 6?6 of the cases. Areas of sclerosis were
seen in 75.5?6 and crescents in 23.496. Morphologic
severity was not related to age. Electron
dense deposits were seen in mesangium in
all cases. with less amounts of subendothelial
deposits in 36%, and subepithelial humps in 6?0.
Clinically the common presentations were
proteinuria, microscopic and gross hematuria.
Nephrotic range proteinuria was seen in 20. 2%,
impaired renal function test in 13.8%, hypertension
in 18.196, and abnormal urinary casts in
18. 15'6 of cases.
It is assumed that IgA nephropathy is fairly
common disease among the Korean population,
and might be the commonest primary glomerular
disease in this country, and it might represent
significant proportion of advanced clinical and
morphological manifestations.
dc.publisher서울대학교 의과대학-
dc.titleIgA Nephropathy-
dc.title.alternativeIg A 신사구체염-
dc.typeSNU Journal-
dc.contributor.AlternativeAuthorLee, Hyun Soon-
dc.contributor.AlternativeAuthorKoh, Haeng Il-
dc.contributor.AlternativeAuthorPark, Han Chul-
dc.citation.journaltitle서울 의대 잡지-
dc.citation.journaltitle서울 의대 학술지-
dc.citation.journaltitleSeoul Journal of Medicine-
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