대량수혈시 혈액응고에 관한 임상적 고찰

Abstract

Studies of blood coagulation parameters were carried out in 20 patients of SNUH who received a large number (6~21 pints) of transfusions of stored blood anticoagulated with acid-citrate-dextrose solution. All patient didn't develop hemorrhagic diathesis, but developed slight dilutional thrombocytopenia (126, 000±58, 000)/mm3 and other test (e.g. PTT, PT, Fibringen, Euglobulin lysis time and FDP test) was within normal limit. It is concluded that although several factors may be involved, dilutional thrombocytopenia due to stored blood is the primary cause of bleeding which follows massive blood transfusions.