S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 05 No.3 (1964)
흰 쥐의 생체밖 소장의 수분 및 전해질 흡수
The Absorption of Water and some Electrolytes from the Isolated Small Intestine of the Rat.
- Issue Date
- 서울대학교 의과대학
- Seoul J Med, Vol.5 No.3, pp. 77-87
- Isolated intestinal loops of 54 rats were perfused
with Krebs·Ringer·bicarbonate-glucose solution under
pressure of 10 or 25 cmH20 at a constant temperature
of 40°C. Among them some loops were everted
and the serosal to mucosal transport was also studied.
The perfusing solution was saturated with 95%02 +
5%C20. Samples collected in the bottom of the
perfusing apparatus were taken with one hour interval.
Following conclusions were made.
1. The amount of fluid transferred related to the
pressure applied and regional differences were
noticed, e.g.. more fluid passed through the
jejunal wall than through the ileum in unit time.
2. In the everted loops less amount of fluid was
transferred than in the uneverted preparations.
3. The osmolality of the transferred fluid was slightly
higher than that of the perfusing fluid, suggesting
some addition of solutes in the course of the passage.
4. Comparingthe constituents of the perfusing and the
transferred fluids, following results were revealed.
a. Transferred fluid had lower concentrations of
sodium, potassium and urea in comparison with
those of the perfusing fluid.
b. Unique characteristics of SCN- was observed
in the transport through the wall of ileum,
having a higher concentration in the transferred
fluid than in the perfusing fluid. Combining
this fact with the lower concentration of SCNin
the ileal wall the presence of organic anions
in abundance in the tissue was suggested.