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Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ko, SG | - |
dc.contributor.author | Kim, HP | - |
dc.contributor.author | Jin, DH | - |
dc.contributor.author | Bae, HS | - |
dc.contributor.author | Kim, SH | - |
dc.contributor.author | Park, CH | - |
dc.contributor.author | Lee, JW | - |
dc.creator | 이정원 | - |
dc.date.accessioned | 2013-04-16T07:52:06Z | - |
dc.date.available | 2013-04-16T07:52:06Z | - |
dc.date.created | 2017-11-15 | - |
dc.date.issued | 2005-03 | - |
dc.identifier.citation | Cancer Letters, Vol.220 No.1, pp.11-19 | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://hdl.handle.net/10371/82047 | - |
dc.description.abstract | The molecular effects of Saussurea lappa extracts, a traditional medicine in Eastern Asia, on the fate of gastric carcinoma have not been understood. In this study, its cytostatic effects were examined using gastric AGS cancer cells. Its treatment resulted in apoptosis and G2-arrest in a dose- and time-dependent manner. The effects were attributed to the regulation of cyclins and pro-apoptotic molecules and suppression of anti-apoptotic molecules. Therefore, these results suggest that extracts of S. lappa root may be a candidate to deal with gastric cancers either by traditional herbal therapy or by combinational therapy with conventional chemotherapy. (c) 2004 Elsevier Ireland Ltd. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | en |
dc.publisher | Elsevier BV | - |
dc.title | Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 고성규 | - |
dc.contributor.AlternativeAuthor | 김황필 | - |
dc.contributor.AlternativeAuthor | 진동훈 | - |
dc.contributor.AlternativeAuthor | 배현수 | - |
dc.contributor.AlternativeAuthor | 김성훈 | - |
dc.contributor.AlternativeAuthor | 박종형 | - |
dc.contributor.AlternativeAuthor | 이정원 | - |
dc.identifier.doi | 10.1016/j.canlet.2004.06.026 | - |
dc.citation.journaltitle | Cancer Letters | - |
dc.identifier.wosid | 000227865500002 | - |
dc.identifier.scopusid | 2-s2.0-14644399795 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2005-01/102/0000003910/1 | - |
dc.description.srnd | SEQ:1 | - |
dc.description.srnd | PERF_CD:SNU2005-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:0000003910 | - |
dc.description.srnd | ADJUST_YN:Y | - |
dc.description.srnd | EMP_ID:A078142 | - |
dc.description.srnd | DEPT_CD:375 | - |
dc.description.srnd | CITE_RATE:3.049 | - |
dc.description.srnd | FILENAME:25KoSG_CL.pdf | - |
dc.description.srnd | DEPT_NM:약학과 | - |
dc.description.srnd | EMAIL:jwl@snu.ac.kr | - |
dc.description.srnd | CONFIRM:Y | - |
dc.citation.endpage | 19 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 11 | - |
dc.citation.volume | 220 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lee, JW | - |
dc.identifier.srnd | 2005-01/102/0000003910/1 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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