고압 및 저압이 조직비판세포에 미치는 영향에 관한 실험적연구

Abstract

The behavior of tissue mast cells in albino rats subjected to experimental pressure change was studied. Compression chamber for small animals was used to maintain 3 atmospheric pressure. and decompression chamber to maintain 18,000 ft. simulated altitude (approximately one-half atmospheric pressure). After exposure to high and low pressure for 7 hours the animals were restored to normal condition. Total mast cells per 20 high power fields were counted in various tissues and organs in relation to time passed after exposures, Both high and low pressure exposures exeted a graduaIr decrease in the mast cell count in various tissues and organs which reached to the minimal level at 6~12 hours and 3~6 hours after exposure. respectively. followed by a gradual rise up to normal level within a week. When the numbers of tissue mast cells in tissues were decreasing in albino-rats under high and low pressure, percentage of normal type of tissue mast cell was decreased while percentage of diffuse type was increased On the other hand. when the numbers of tissue mast cells were restored and increased. the percentage of the Icrrnr rs increased and that of the latters decreased. Summarizing the experimental results stated above. it was assumed that the numerical changes of tissue mast cells in rat are in certain relationship with pressure changes.