갑상선종 환자의 안증상

Abstract

The ocular changes in thyrotoxicosis were investigated in 53 patients who were referred from the Isotope Clinic of this university. The incidence of thyrotoxicosis was about four times as great in females as in males with the greatest frequency at about the third decade of life in both sex. About 20% of the cases showed exophthalmos which occurred in patients whose duration of goiter was more than 3 years and who have been given medical treatment previously. The palpebral fissure was abnormally wide in 23 %, and lid retraction was found only in I case, whereas the lid lag was noted in 7 patients. Power of convergence was insufficient in 55%. The incidence of one or more ocular changes was 75.7% and is greater in diffuse goiter than in nodular form. These facts well agree with the reported observations. The intraocular pressure and scleral rigidity rema· 'ned within the normal ranges and visual fields for 3/1. 000 red and blue were within normal limits. Of the 15 patients who were treated with radioiodine- Ldl and followed for 2-8 months, exophthalmos increased in 47% and improved in 20%. The width of the palpebral fissure and near point of convergence improved much better than proptosis., However, lid retraction and lid lag tend to persist after control of systemic toxicosis. No significant change was noted in intraocular pressure and scleral rigidity. Ocular manifestations are found not to be related to the severity of the systemic toxic signs and syrnptoms. In 41 non·toxic goiter, clinically similar ocular changes, except lid retraction and lid lag, were observed with less frequency. The results of the treatment with radio-iodine showed the same tendency as found in the toxic goiter.