Publications
Detailed Information
Very virulent infectious bursal disease virus isolated from wild birds in Korea: Epidemiological implications
Cited 22 time in
Web of Science
Cited 25 time in Scopus
- Authors
- Issue Date
- 2008-08-08
- Publisher
- Elsevier
- Citation
- Virus Research 137, 153-156
- Keywords
- Infectious bursal disease ; VP2 ; Wild birds ; Very virulent IBDV
- Abstract
- To explore the epidemiological link between infectious bursal disease virus (IBDV) in wild birds and domestic chickens in Korea, we examined 107 free-living wild birds, representing 7 species, that were found dead of apparent natural causes in Korea over the past two years for the presence of IBDV. Five birds were tested positive for IBDV by RT-PCR assay: black-billed magpie (n = 1), mallard duck (n = 2), bean goose (n = 1) and white-fronted goose (n = 1). IBDV was isolated from RT-PCR-positive tissues following chicken embryo inoculation. Sequence analysis of the VP2 gene indicated that all of the isolates from the wild birds encode amino acids A222, I242, I256, I294 and S299 of VP2, which are conserved among strains of very virulent IBDV (vvIBDV). Phylogenetic analysis revealed that the wild bird IBDV isolates are closely related to strains of vvIBDV. An IBDV isolate from a magpie showed 60% mortality in SPF chickens and severe bursal atrophy. The epidemiological implications of IBDV in free-living wild birds are discussed. To our knowledge, this is the first report of vvIBDV in free-living wild birds.
- ISSN
- 0168-1702
- Language
- English
- Files in This Item:
- There are no files associated with this item.
- Appears in Collections:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.