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Isolation and characterization of a Myoviridae bacteriophage against Staphylococcus aureus isolated from dairy cows with mastitis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Han, Jee Eun | - |
dc.contributor.author | Kim, Ji Hyung | - |
dc.contributor.author | Hwang, Sun Young | - |
dc.contributor.author | Choresca Jr., Casiano H. | - |
dc.contributor.author | Jun, Jin Woo | - |
dc.contributor.author | Chai, Ji Young | - |
dc.contributor.author | Park, Yong Ho | - |
dc.contributor.author | Park, Se Chang | - |
dc.contributor.author | Shin, Sang Phil | - |
dc.creator | 박세창 | - |
dc.date.accessioned | 2013-10-10T01:26:55Z | - |
dc.date.available | 2013-10-10T01:26:55Z | - |
dc.date.issued | 2013-10 | - |
dc.identifier.citation | Research in Veterinary Science Vol.95 No.2, pp. 758-763 | - |
dc.identifier.issn | 0034-5288 | - |
dc.identifier.uri | https://hdl.handle.net/10371/83599 | - |
dc.description.abstract | A lytic bacteriophage (phage), designated SAH-1, was isolated from sewage effluent near a dairy cow farm in Gwacheon, South Korea to search for biocontrol agents against Staphylococcus aureus infections. The SAH-1 was morphologically classified as Myoviridae and possessed an approximate 144 kb double-stranded genomic DNA. The phage showed broad host ranges within S. aureus strains including methicillin-resistant strains, and its latent period and burst size were approximately 20 min and 100 PFU/cell, respectively. Moreover, morphologic and genomic analysis of SAH-1 revealed that the phage was closely related to other Myoviridae phages infecting Staphylococcus species. The bacteriolytic activity of phage SAH-1 at a multiplicity of infection (MOI) 1 and 100 indicated its efficiency for reducing bacterial growth. Based on these results, phage SAH-1 could be considered a potential therapeutic or prophylactic candidate against S. aureus infections. | - |
dc.description.sponsorship | This study was financially supported by a Korean Research Foundation Grant (KRF-2008-331-E00385). | - |
dc.language.iso | en | en |
dc.publisher | Elsevier Ltd. | en |
dc.subject | 농수해양 | en |
dc.subject | Bacteriophage | - |
dc.subject | Mastitis | - |
dc.subject | Myoviridae | - |
dc.subject | SAH-1 | - |
dc.subject | Staphylococcus aureus | - |
dc.title | Isolation and characterization of a Myoviridae bacteriophage against Staphylococcus aureus isolated from dairy cows with mastitis | en |
dc.type | Article | - |
dc.author.alternative | 한지은 | - |
dc.author.alternative | 김지형 | - |
dc.author.alternative | 황선영 | - |
dc.author.alternative | 신상필 | - |
dc.author.alternative | 전진우 | - |
dc.author.alternative | 채지영 | - |
dc.author.alternative | 박용호 | - |
dc.author.alternative | 박세창 | - |
dc.identifier.doi | 10.1016/j.rvsc.2013.06.001 | - |
dc.citation.journaltitle | Research in Veterinary Science | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2013-01/102/0000030777/8 | - |
dc.description.srnd | SEQ:8 | - |
dc.description.srnd | PERF_CD:SNU2013-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:0000030777 | - |
dc.description.srnd | ADJUST_YN:N | - |
dc.description.srnd | EMP_ID:A076079 | - |
dc.description.srnd | DEPT_CD:551 | - |
dc.description.srnd | CITE_RATE:1.649 | - |
dc.description.srnd | FILENAME:1-s2.0-s0034528813002002-main.pdf | - |
dc.description.srnd | DEPT_NM:수의학과 | - |
dc.description.srnd | EMAIL:parksec@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | CONFIRM:Y | - |
dc.identifier.srnd | 2013-01/102/0000030777/8 | - |
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