S-Space College of Engineering/Engineering Practice School (공과대학/대학원) Dept. of Mechanical Aerospace Engineering (기계항공공학부) Journal Papers (저널논문_기계항공공학부)
Molded nanowell electrodes for site-selective single liposome arrays
- Kim, Pilnam; Lee, Bong Kuk; Lee, Hea Yeon; Kawai, Tomoji; Suh, Kahp Y.
- Issue Date
- Adv. Mater. 2008, 20, 31
- SELF-ASSEMBLED MONOLAYERS; DIP-PEN NANOLITHOGRAPHY; LIPID-BILAYERS; PHOSPHOLIPID-MEMBRANES; PROTEIN INTERACTIONS; CARBON NANOTUBES; BIOSENSORS; PHOTOLITHOGRAPHY; MICROSTRUCTURES; LITHOGRAPHY
- We present a nanowell (NW)-based biosensing platform for electrochemically detecting biological reactions on the level of single lipid vesicle. The NW geometry of a gently-sloped vertical wall is found to be optimal for selective deposition of single liposomes without capillary resistances. Also, the use of a hydrophilic, non-biofouling PEG copolymer is essential to provide distinctively separated FLV arrays without nonspecific adsorption.
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