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Molded nanowell electrodes for site-selective single liposome arrays

Cited 28 time in Web of Science Cited 28 time in Scopus
Authors
Kim, Pilnam; Lee, Bong Kuk; Lee, Hea Yeon; Kawai, Tomoji; Suh, Kahp Y.
Issue Date
2008-01-07
Publisher
Wiley-Blackwell
Citation
Adv. Mater. 2008, 20, 31
Keywords
SELF-ASSEMBLED MONOLAYERSDIP-PEN NANOLITHOGRAPHYLIPID-BILAYERSPHOSPHOLIPID-MEMBRANESPROTEIN INTERACTIONSCARBON NANOTUBESBIOSENSORSPHOTOLITHOGRAPHYMICROSTRUCTURESLITHOGRAPHY
Abstract
We present a nanowell (NW)-based biosensing platform for electrochemically detecting biological reactions on the level of single lipid vesicle. The NW geometry of a gently-sloped vertical wall is found to be optimal for selective deposition of single liposomes without capillary resistances. Also, the use of a hydrophilic, non-biofouling PEG copolymer is essential to provide distinctively separated FLV arrays without nonspecific adsorption.
ISSN
0935-9648
Language
English
URI
https://hdl.handle.net/10371/8373
DOI
https://doi.org/10.1002/adma.200700570
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Mechanical Aerospace Engineering (기계항공공학부)Journal Papers (저널논문_기계항공공학부)
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