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Genetic analysis and pathogenicity of betanodavirus isolated from wild redspotted grouper Epinephelus akaara with clinical signs

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dc.contributor.authorGomez, Dennis K.-
dc.contributor.authorMatsuoka, Satoru-
dc.contributor.authorMori, Koh-ichiro-
dc.contributor.authorOkinaka, Yasushi-
dc.contributor.authorPark, Se Chang-
dc.contributor.authorNakai, Toshihiro-
dc.date.accessioned2009-09-03T22:53:44Z-
dc.date.available2009-09-03T22:53:44Z-
dc.date.issued2009-01-08-
dc.identifier.citationArch Virol 154:343-346en
dc.identifier.issn0304-8608 (print)-
dc.identifier.issn1432-8798 (online)-
dc.identifier.urihttps://hdl.handle.net/10371/8618-
dc.description.abstractDiseased wild redspotted grouper Epinephelus akaara were collected from Seto Inland Sea, Ehime Prefecture, in August 2002. Fish showed erratic swimming behavior and inflation of the swim bladder. The fish brains were positive for nodavirus in both RT-PCR and nested PCR. The sequence of the nested PCR product (177 nt) was closely related to that of a known betanodavirus, redspotted grouper nervous necrosis virus. When juvenile sevenband grouper E. septemfasciatus were challenged intravitreously with virus, abnormal swimming behavior and high mortality were observed. This is the first report on viral nervous necrosis in a wild population of redspotted grouper with clinical signs.en
dc.description.sponsorshipThis study was supported in part by a Grant-in-
Aid Scientific Research (B) (16380132) from Ministry of Education,
Culture, Sports, Science and Technology, Japan.
en
dc.language.isoen-
dc.publisherSpringer Verlagen
dc.titleGenetic analysis and pathogenicity of betanodavirus isolated from wild redspotted grouper Epinephelus akaara with clinical signsen
dc.typeArticleen
dc.contributor.AlternativeAuthor박세창-
dc.identifier.doi10.1007/s00705-008-0305-5-
Appears in Collections:
College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
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