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Chronic Cellular Reactions to Silicon Neural Probe Implant
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, Seung Jae | - |
dc.contributor.author | Song, Jong Keun | - |
dc.contributor.author | Bjornsson, CS | - |
dc.contributor.author | Al-Kohafi, Y | - |
dc.contributor.author | Smith, Karen L. | - |
dc.contributor.author | Turner, James | - |
dc.contributor.author | Shain, William | - |
dc.contributor.author | Kim, Sung June | - |
dc.date.accessioned | 2009-09-11 | - |
dc.date.available | 2009-09-11 | - |
dc.date.issued | 2006-07-04 | - |
dc.identifier.citation | 5th International Meeting on Substrate-Integrated Micro Electrode Arrays (MEA Meeting 2006), Reutlingen, Germany, July 4-7, 2006 | en |
dc.identifier.uri | https://hdl.handle.net/10371/9123 | - |
dc.description.abstract | Chronic use of micromachined silicon neural probes is limited due to the formation of a complex
sheath of cells and extracellular proteins that electrically isolates devices from adjacent neurons and neuronal damage. Understanding device-tissue interactions in the brain will provide a basis for developing successful interface strategies for biocompatible microdevices. While the reactive responses to single shank silicon devices inserted into neocortex are well characterized, responses in other regions have not been described. This study was designed to determine if the reactive responses observed in hippocampus and thalamus are similar to those observed in neocortex. This information is necessary to design and implement appropriate intervention strategies to control regional cell and tissue responses. Study of responses in hippocampus and thalamus has important scientific and clinical implications. | en |
dc.description.sponsorship | This work was supported by the International
Collaboration Program, NBS-ERC (Nano Bioelectronics and Systems Engineering Research Center)/ KOSEF (Korea Science and Engineering Foundation) and also supported in part by the Nanobiotechnology Center (NBTC), an STC Program of the National Science Foundation under Agreement No. ECS-9876771. | en |
dc.language.iso | en | en |
dc.title | Chronic Cellular Reactions to Silicon Neural Probe Implant | en |
dc.type | Conference Paper | en |
dc.contributor.AlternativeAuthor | 오승재 | - |
dc.contributor.AlternativeAuthor | 송종근 | - |
dc.contributor.AlternativeAuthor | 김성준 | - |
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