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Epidural adhesiolysis complicated by cefazolin-induced status epilepticus: Two cases

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Authors
Choi, Jeong-Yoon; Seok, Hung Youl; Lee, Sang-Heon; Kim, Byung-Jo; Park, Kun-Woo; Jung, Ki-Young
Issue Date
2008-12
Publisher
Elsevier
Citation
Clinical Neurology and Neurosurgery, Vol.110 No.10, pp. 1041-1043
Keywords
의약학Status epilepticusCefazolinIntrathecal injectionAdverse effects
Abstract
Cefazolin is a strong epileptogenic agent. We describe two patients presenting with status epilepticus, apparently caused by intrathecal leakage of cefazolin via incidental dural puncture during spinal epidural adhesiolysis. Our cases suggest that the local use of antibiotics, particularly cefazolin, in the form of a mixture with contrast medium during a spinal procedure is not advisable, because of the possible incidental intrathecal leakage and the high convulsive potential of the antibiotics.
ISSN
0303-8467
Language
English
URI
http://hdl.handle.net/10371/91778
DOI
https://doi.org/10.1016/j.clineuro.2008.06.007
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
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