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Effects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trial

DC Field Value Language
dc.contributor.authorYeo, Hye-Bin-
dc.contributor.authorYoon, Ho-Kyoung-
dc.contributor.authorLee, Heon-Jeong-
dc.contributor.authorKang, Seung-Gul-
dc.contributor.authorJung, Ki-Young-
dc.contributor.authorKim, Leen-
dc.creator정기영-
dc.date.accessioned2014-05-15T07:00:44Z-
dc.date.available2014-05-15T07:00:44Z-
dc.date.issued2012-04-
dc.identifier.citationJournal of Ginseng Research, Vol.36 No.2, pp. 190-197-
dc.identifier.issn1226-8453-
dc.identifier.urihttps://hdl.handle.net/10371/91788-
dc.description.abstractGinseng has a long history of use for health enhancement, and there is some evidence from animal studies that it has a beneficial effect on cognitive performance. The purpose of this study was to investigate the effect of Korean red ginseng on cognitive performance in humans. A total of 15 healthy young males with no psychiatric or cognitive problems were selected based on an interview with a board-certified psychiatrist. The subjects were randomly assigned to receive a daily dose of 4,500 mg red ginseng or placebo for a 2-week trial. There were 8 subjects in the red ginseng group and 7 subjects in the placebo group. All of the subjects were analyzed with the Vienna test system and a P300 event-related potential (ERP) test. There were no significant differences in the Vienna test system scores between the red ginseng group and the placebo group. In the event-related potential test, the C3 latency of the red ginseng group tended to decrease during the study period (p=0.005). After 2 wk, significant decreases were observed in the P300 latencies at Cz (p=0.008), C3 (p=0.005), C4 (p=0.002), and C mean (p=0.003) in the red ginseng group. Our results suggest that the decreased latency in ERP is associated with improved cognitive function. Further studies with a higher dosage of ginseng, a larger sample size, and a longer follow-up period are necessary to confirm the clinical efficacy of Korean red ginseng.en
dc.language.isoenen
dc.publisherKorean Society of Ginsengen
dc.subject의약학en
dc.subjectPanax ginseng-
dc.subjectCognitive and motor function-
dc.subjectEvoked potentials-
dc.subjectKorean red ginseng-
dc.subjectVienna test system-
dc.titleEffects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trialen
dc.typeArticle-
dc.contributor.AlternativeAuthor여혜빈-
dc.contributor.AlternativeAuthor윤호경-
dc.contributor.AlternativeAuthor이헌정-
dc.contributor.AlternativeAuthor강승걸-
dc.contributor.AlternativeAuthor정기영-
dc.contributor.AlternativeAuthor김린-
dc.identifier.doi10.5142/jgr.2012.36.2.190-
dc.description.srndOAIID:oai:osos.snu.ac.kr:snu2012-01/102/2014017262/7-
dc.description.srndSEQ:7-
dc.description.srndPERF_CD:SNU2012-01-
dc.description.srndEVAL_ITEM_CD:102-
dc.description.srndUSER_ID:2014017262-
dc.description.srndADJUST_YN:Y-
dc.description.srndEMP_ID:A079623-
dc.description.srndDEPT_CD:801-
dc.description.srndCITE_RATE:0-
dc.description.srndDEPT_NM:의학과-
dc.description.srndSCOPUS_YN:N-
dc.description.srndCONFIRM:Y-
dc.identifier.srnd2012-01/102/2014017262/7-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
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