신장의 혈류량 자동조절에 관한 실험적 연구

Abstract

The phenomenon of renal autoregulation was investigated in the rabbits weighed from 1.8 to 2.3 kg. An isolated kidney from a experimental rabbit was perfused with the blood coIIected from the other one rabbit and the renal blood flow was measured in various arterial perfusion pressures. From the perfusion studies in connection of the isolated rabbit kidney with the perfusion system, foIIowing results were obtained: 1) The autoregulation was continued for 30 minutes from the time of perfusi~n ， and deteriora tion was noted rapidly. 2) The change in kidney weight was noted after the experiment. The increase in weight was revealed by the 3.2%. (from 6.54 gm to 6.75 gm) 3) The range of autoregulation was from the 110• 120 mmHg of renal perfusion pressure to the 180• 190 mmHg. 4) Within the range of autoregulation, the mean renal blood flow was 1.25 mljgm/min. 5) Total renal resistance calculated was increased proportionately within the range of autoregulation. However, that was inversely related to changes in renal perfusion pressure.