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dbCRY: aWeb-based comparative and evolutionary genomics platform for blue-light receptors

DC Field Value Language
dc.contributor.authorChoi, Jaeyoung-
dc.contributor.authorLee, Hye-Young-
dc.contributor.authorLee, Gir-Won-
dc.contributor.authorLee, Yong-Hwan-
dc.contributor.authorChoi, Doil-
dc.creator최도일-
dc.date.accessioned2014-06-17T05:10:39Z-
dc.date.available2014-06-17T05:10:39Z-
dc.date.issued2014-05-
dc.identifier.citationDatabase, 2014, bau037-
dc.identifier.issn1758-0463-
dc.identifier.urihttps://hdl.handle.net/10371/92278-
dc.description.abstractCryptochromes are flavoproteins that play a central role in the circadian oscillations of all living organisms except archaea. Cryptochromes are clustered into three subfamilies: plant-type cryptochromes, animal-type cryptochromes and cryptochrome-DASH proteins. These subfamilies are composed of photolyase/cryptochrome superfamily with 6–4 photolyase and cyclobutane pyrimidine dimer photolyase. Cryptochromes have conserved domain architectures with two distinct domains, an N-terminal photolyase-related domain and a C-terminal domain. Although the molecular function and domain architecture of cryptochromes are conserved, their molecular mechanisms differ between plants and animals. Thus, cryptochromes are one of the best candidates for comparative and evolutionary studies. Here, we have developed a Web-based platform for comparative and evolutionary studies of cryptochromes, dbCRY (http://www.dbcryptochrome.org/). A pipeline built upon the consensus domain profile was applied to 1438 genomes and identified 1309 genes. To support comparative and evolutionary genomics studies, the Web interface provides diverse functions such as (i) browsing by species, (ii) protein domain analysis, (iii) multiple sequence alignment, (iv) homology search and (v) extended analysis opportunities through the implementation of Favorite Browser powered by the Comparative Fungal Genomics Platform 2.0 (CFGP 2.0; http://cfgp.snu.ac.kr/). dbCRY would serve as a standardized and systematic solution for cryptochrome genomics studies.en
dc.language.isoenen
dc.publisherOxford University Pressen
dc.subject농수해양en
dc.titledbCRY: aWeb-based comparative and evolutionary genomics platform for blue-light receptorsen
dc.typeArticle-
dc.contributor.AlternativeAuthor김용민-
dc.contributor.AlternativeAuthor최재영-
dc.contributor.AlternativeAuthor이혜영-
dc.contributor.AlternativeAuthor이거원-
dc.contributor.AlternativeAuthor이용환-
dc.identifier.doi10.1093/database/bau037-
dc.description.srndOAIID:oai:osos.snu.ac.kr:snu2014-01/102/0000005113/9-
dc.description.srndSEQ:9-
dc.description.srndPERF_CD:SNU2014-01-
dc.description.srndEVAL_ITEM_CD:102-
dc.description.srndUSER_ID:0000005113-
dc.description.srndADJUST_YN:N-
dc.description.srndEMP_ID:A077085-
dc.description.srndDEPT_CD:517-
dc.description.srndCITE_RATE:4.2-
dc.description.srndFILENAME:db-cry.pdf-
dc.description.srndDEPT_NM:식물생산과학부-
dc.description.srndSCOPUS_YN:Y-
dc.description.srndCONFIRM:Y-
dc.identifier.srnd2014-01/102/0000005113/9-
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