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Association between red blood cell storage duration and clinical outcome in patients undergoing off-pump coronary artery bypass surgery: a retrospective study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Min, Jeong Jin | - |
dc.contributor.author | Bae, Jun-Yeol | - |
dc.contributor.author | Kim, Tae Kyong | - |
dc.contributor.author | Hong, Deok Man | - |
dc.contributor.author | Hwang, Ho Young | - |
dc.contributor.author | Kim, Ki-Bong | - |
dc.contributor.author | Han, Kyou-Sup | - |
dc.contributor.author | Jeon, Yunseok | - |
dc.date.accessioned | 2014-10-28T08:51:24Z | - |
dc.date.available | 2014-10-28T08:51:24Z | - |
dc.date.issued | 2014-10-21 | - |
dc.identifier.citation | BMC Anesthesiology. 2014, 14 : 95 | ko_KR |
dc.identifier.uri | https://hdl.handle.net/10371/93462 | - |
dc.description.abstract | Background: Prolonged storage of red blood cells (RBCs) leads to fundamental changes in both the RBCs and the storage media. We retrospectively evaluated the relationship between the RBC age and in-hospital and long-term postoperative outcomes in patients undergoing off-pump coronary artery bypass.
Methods: The electronic medical records of 1,072 OPCAB patients were reviewed and information on the transfused RBCs and clinical data were collected. The effects of RBCs age (mean age, oldest age of transfused RBCs, any RBCs older than 14 days) on various in-hospital postoperative complications and long-term major adverse cardiovascular and cerebral events over a mean follow-up of 31 months were investigated. Correlations between RBCs age and duration of intubation, intensive care unit, or hospital stay, and base excess at the first postoperative morning were also analyzed. Results: After adjusting for confounders, there was no relationship between the RBCs age and in-hospital and long-term clinical outcomes except for postoperative wound complications. A significant linear trend was observed between the oldest age quartiles of transfused RBCs and the postoperative wound complications (quartile 1 vs. 2, 3 and 4: OR, 8.92, 12.01 and 13.79, respectively; P for trend = 0.009). The oldest transfused RBCs showed significant relationships with a first postoperative day negative base excess (P = 0.021), postoperative wound complications (P = 0.001), and length of hospital stay (P = 0.008). Conclusions: In patients undergoing off-pump coronary artery bypass, the oldest age of transfused RBCs were associated with a postoperative negative base excess, increased wound complications, and a longer hospital stay, but not with the other in-hospital or long-term outcomes. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | RBC storage age | ko_KR |
dc.subject | Old stored RBC | ko_KR |
dc.subject | Postoperative outcome | ko_KR |
dc.subject | Wound complication | ko_KR |
dc.subject | Cardiac surgery | ko_KR |
dc.title | Association between red blood cell storage duration and clinical outcome in patients undergoing off-pump coronary artery bypass surgery: a retrospective study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 민정민 | - |
dc.contributor.AlternativeAuthor | 배준열 | - |
dc.contributor.AlternativeAuthor | 김태경 | - |
dc.contributor.AlternativeAuthor | 홍덕만 | - |
dc.contributor.AlternativeAuthor | 황호영 | - |
dc.contributor.AlternativeAuthor | 김기봉 | - |
dc.contributor.AlternativeAuthor | 한규섭 | - |
dc.contributor.AlternativeAuthor | 전윤석 | - |
dc.identifier.doi | 10.1186/1471-2253-14-95 | - |
dc.language.rfc3066 | en | - |
dc.description.version | Peer Reviewed | - |
dc.rights.holder | Jeong Jin Min et al.; licensee BioMed Central Ltd. | - |
dc.date.updated | 2014-10-24T03:04:05Z | - |
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