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Paraneoplastic downbeat nystagmus associated with cerebellar hypermetabolism especially in the nodulus

Cited 5 time in Web of Science Cited 4 time in Scopus
Authors
Choi, Seo Young; Park, Seong-Ho; Kim, Hyo-Jung; Kim, Ji-Soo
Issue Date
2014-08
Publisher
Elsevier
Citation
Journal of the Neurological Sciences, Vol.343 No.1-2, pp. 187-191
Keywords
복합학Downbeat nystagmusParaneoplastic syndromeVertigoAtaxia
Abstract
A 52-year-old man with vertigo and imbalance for two weeks showed spontaneous downbeat (DBN), horizontal gaze-evoked, and positional apogeotropic nystagmus along with severe limb and truncal ataxia. Gadolinium-enhanced brain MRI was normal, but whole body and brain 2-deoxy-2-[F18]fluoro-D-glucose-positron emission tomography revealed hypermetabolism in the right lower lobe of the lung and the cerebellum, especially in the nodulus. The lesion in the lung was confirmed as mixed cell carcinoma. Paraneoplastic DBN may be associated with cerebellar hypermetabolism, especially in the nodulus.
ISSN
0022-510X
Language
English
URI
https://hdl.handle.net/10371/94242
DOI
https://doi.org/10.1016/j.jns.2014.05.030
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
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