Browse

Relationships Between State and Trait Anxiety Inventory and Alcohol Use Disorder Identification Test Scores Among Korean Twins and Families: The Healthy Twin Study

Cited 9 time in Web of Science Cited 8 time in Scopus
Authors
Sung, Joohon; Lee, Kayoung; Song, Yun-Mi; Kim, Ji-Hae
Issue Date
2011-02
Publisher
Cambridge University Press
Citation
Twin Research and Human Genetics, Vol.14 No.1, pp. 73-78
Keywords
복합학state anxietytrait anxietyalcoholheritabilitygenetic correlation
Abstract
We explored heritabilities of the State and Trait Anxiety Inventory (STAI) and the Alcohol Use Disorders Identification Test (AUDIT), and associations including genetic and environmental correlations between the phenotypes among Korean twins and their families. We analyzed the data of 1,748 participants (835 men, 913 women, 656 individuals of monozygotic twins, 173 individuals of same-sexed dizygotic twins, 919 non-twin family members, age 30-79 years) from the Healthy Twin study. Heritabilities and bivariate analyses were assessed using the SOLAR package software. In the methods of generalized estimation equations, women in the 4th quartile of state and trait scores were 17% and 15%, respectively more likely to be hazardous alcohol users compared to women in the lower three quartiles (P < .05). However, there were no significant associations between these phenotypes in men. After adjusting for age and squared age, the heritability estimates were 0.26 in men and 0.34 in women for the state score; for the trait score, 0.35 in men and 0.31 in women; for the AUDIT score, 0.32 in men and 0.37 in women (P < .001). After adjusting for age and squared age, there was a significant genetic correlation between the trait score and the AUDIT score, and a significant non-genetic correlation between the state score and the AUDIT score in women, while there were no significant genetic or non-genetic correlations between these phenotypes in men. The STAI and AUDIT scores are heritable in Koreans and the relationships between these phenotypes may be inconsistent by sex.
ISSN
1832-4274
Language
English
URI
https://hdl.handle.net/10371/94261
DOI
https://doi.org/10.1375/twin.14.1.73
Files in This Item:
There are no files associated with this item.
Appears in Collections:
Graduate School of Public Health (보건대학원)Dept. of Public Health (보건학과)Journal Papers (저널논문_보건학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse