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뇌혈류량에 영향을 주는 각종인자 : Cerebral Blood Flow and its Change by the Various Affectirg Factors in the Dog
DC Field | Value | Language |
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dc.contributor.author | 주종구 | - |
dc.contributor.author | 김우겸 | - |
dc.date.accessioned | 2009-09-16T03:17:15Z | - |
dc.date.available | 2009-09-16T03:17:15Z | - |
dc.date.issued | 1975-09 | - |
dc.identifier.citation | Seoul J Med, Vol.16 No.3, pp. 184-192 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/9433 | - |
dc.description.abstract | Cerebral blood flow and cardiovascular hemodynamics
and its change were determined under the various conditions in the dog. Cerebral blood flow was measured using rotameter and cardiac output was measured analyzing the saline dilution curve, recorded on physiograph the extra-arterial conductivity, using Stewart-Hamilton formula. 1. Cerebral blood flow through the one side of internal carotid was 57.7 ml in 9 dogs (13. 8- 19. 2 kg body weight). Cardiac index in the dog was 131 ml/min/kg. Arterial blood pressure and cerebral vascular resistance were 117 mmHg and 2.03 mmHg/ml/min, respectively. 2. Raising the arterial blood pressure up to 164 mmHg by the constant infusion of epinephrine, cerebral blood flow did not show any significant change. Lowering the arterial blood pressure from 146 mmHg to 50 mmHg , by the serial blood loss from the vein , cerebral blood flow main tained fairly steady level, however, lower than 68 mmHg of arterial blood pressure, there was an abrupt decrease of cerebral vascular resistance. This might suggest that this range of the pressure might be the autoregulatory limit of the cerebral circulation. 3. Hyperventilation did not produce any change in cardiovascular hemodynamics and cerebral blood flow. On the contrary, breathing with 5% CO,-O, mixture. cerebral blood flow increased from 60.1 ml/min to 68.6 ml/min, associated with the pH change from 7.40 of normal to 7. 17, and 49 mmHg of arterial CO, tension. 4. Cerebral blood flow increased most eminently after the infusion of hydrochloric acid. Cerebral blood flow increased from 55. I ml!min of normal to 56.8, 66.9, 99.0 ml/min, respectively, with the associated decrease of arterial pH from 7.45 of normal to 7.37. 7.26, 7.18. , respectively. Considering with the hypercapneic effect which has the same pH value. it appears that metabolic acidosis has much mote effectiveness to the cerebral vascular resistance. There was not any cardiovascular effect in metabolic alkalosis. | - |
dc.language.iso | ko | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | 뇌혈류량에 영향을 주는 각종인자 | - |
dc.title.alternative | Cerebral Blood Flow and its Change by the Various Affectirg Factors in the Dog | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | Chu, Chong Ku | - |
dc.contributor.AlternativeAuthor | Kim, Woo Gyeum | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 192 | - |
dc.citation.number | 3 | - |
dc.citation.pages | 184-192 | - |
dc.citation.startpage | 184 | - |
dc.citation.volume | 16 | - |
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