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A prospective randomized clinical trial comparing bone union rate following anterior cervical discectomy and fusion using a polyetheretherketone cage: Hydroxyapatite/B-Tricalcium phosphate mixture versus hydroxyapatite/demineralized bone matrix mixture
DC Field | Value | Language |
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dc.contributor.author | Yi, Jemin | - |
dc.contributor.author | Lee, Gun Woo | - |
dc.contributor.author | Nam, Woo Dong | - |
dc.contributor.author | Han, Kye Young | - |
dc.contributor.author | Kim, Myung-Ho | - |
dc.contributor.author | Kang, Jong Won | - |
dc.contributor.author | Won, Jonghwa | - |
dc.contributor.author | Kim, Seong Wan | - |
dc.contributor.author | Noh, Won | - |
dc.contributor.author | Yeom, Jin S | - |
dc.date.accessioned | 2015-12-11T08:48:12Z | - |
dc.date.available | 2015-12-11T08:48:12Z | - |
dc.date.created | 2018-11-01 | - |
dc.date.issued | 2015-02 | - |
dc.identifier.citation | Asian Spine Journal, Vol.9 No.1, pp.30-38 | - |
dc.identifier.issn | 1976-1902 | - |
dc.identifier.uri | https://hdl.handle.net/10371/94775 | - |
dc.description.abstract | Study Design: Prospective randomized noninferiority trial. Purpose: To evaluate whether the union rate of anterior cervical discectomy and fusion (ACDF) using a polyetheretherketone (PEEK) cage filled with a mixture of hydroxyapatite (HA) and demineralized bone matrix (DBM) is inferior to that of a mixture of β-tricalcium phosphate (β-TCP) and HA. Overview of Literature: There have been no clinical trials investigating the outcomes of a mixture of HA and DBM in a PEEK cage in ACDF. Methods: Eighty-five eligible patients were randomly assigned to group B (n=43), in which a PEEK cage with a mixture of HA and DBM was used, or group C (n=42), in which a PEEK cage with a mixture of HA and β-TCP was used. The primary study endpoint was the fusion rate, which was assessed with dynamic radiographs and computed tomography (CT) scans. Secondary endpoints included pain intensity using a visual analogue scale, functional outcome using a neck disability index score, laboratory tests of inflammatory profiles, and the infection rate. Results: Seventy-seven patients (38 in group B and 39 in group C) were included in the final analysis. One year postoperatively, bone fusion was achieved in 87% of group B patients and 87% of group C patients on dynamic radiographs, and 87% of group B patients and 72% of group C patients on CT scans (p =1.00 and 0.16, respectively). There were also no between-groups differences with respect to the secondary endpoints. Conclusions: A HA/DBM mixture inside a PEEK cage can provide noninferior outcomes compared to a HA/TCP mixture in ACDF. © 2015 by Korean Society of Spine Surgery. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한척추외과학회 | - |
dc.title | A prospective randomized clinical trial comparing bone union rate following anterior cervical discectomy and fusion using a polyetheretherketone cage: Hydroxyapatite/B-Tricalcium phosphate mixture versus hydroxyapatite/demineralized bone matrix mixture | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 이제민 | - |
dc.contributor.AlternativeAuthor | 이건우 | - |
dc.contributor.AlternativeAuthor | 남우동 | - |
dc.contributor.AlternativeAuthor | 한계영 | - |
dc.contributor.AlternativeAuthor | 김명호 | - |
dc.contributor.AlternativeAuthor | 강종원 | - |
dc.contributor.AlternativeAuthor | 원종화 | - |
dc.contributor.AlternativeAuthor | 김성완 | - |
dc.contributor.AlternativeAuthor | 노원 | - |
dc.contributor.AlternativeAuthor | 염진섭 | - |
dc.identifier.doi | 10.4184/asj.2015.9.1.30 | - |
dc.citation.journaltitle | Asian Spine Journal | - |
dc.identifier.wosid | 000420340000005 | - |
dc.identifier.scopusid | 2-s2.0-84923117854 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2015-01/102/0000004226/11 | - |
dc.description.srnd | ADJUST_YN:N | - |
dc.description.srnd | EMP_ID:A079510 | - |
dc.description.srnd | DEPT_CD:801 | - |
dc.description.srnd | CITE_RATE:0 | - |
dc.description.srnd | FILENAME:asj-2015_yi_a prospective randomized clinical trial comparing bone union rate following anterior cervical discectomy.pdf | - |
dc.description.srnd | DEPT_NM:의학과 | - |
dc.description.srnd | CONFIRM:Y | - |
dc.citation.endpage | 38 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 30 | - |
dc.citation.volume | 9 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Yeom, Jin S | - |
dc.identifier.srnd | 2015-01/102/0000004226/11 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordAuthor | Anterior cervical discectomy and fusion | - |
dc.subject.keywordAuthor | Betatricalcium phosphate | - |
dc.subject.keywordAuthor | Demineralized bone matrix | - |
dc.subject.keywordAuthor | Hydroxyapatites | - |
dc.subject.keywordAuthor | Polyetheretherketone cage | - |
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