망막 혈관 폐쇄의 실험적 연구

Abstract

Experimental occlusion of the retinal vessels of rabbit eye was induced by coagulating them at the disc margin with MIRA endodiathermy inserted into the vitreous cavity through the inferior temporal epuator of the eyeball. The fundus changes, electroretinographic changes were observed at regular intervals for three weeks after coagulation of the retinal vessels. There was no significant difference between the occlusion of both central retinal artery and central retinal vein and of the central retinal vein alone The following results were ohtained; 1. Fundus changes are ischemic in nature such as retinal edema, optic di;;c edema, retinal hemorrhages. These changes are confined to the medullary nerve fiber layer which is supplied by the central retinal vessels 2. Immediately after the coagulation of the retinal vessels, b wave amplitude was increased. But there was no specific relationship between the central retinal vessels occlusion and electroretinographic findings in this study. The electroretinographic changes were normalized one day after coagulation 3. Pathologic study showed the edema of the nerve fiber layer and degenerative changes of the ganglion cells.