근종자궁의 혈관변화에 관한 병리조직학적 연구

Abstract

Histopathological investigation of vascular changes in the endo·and myometrium were made on 30 myo matatis and 21 nonmyomatous uteri. Sections were taken from the definite sites of the endo-and myometrium and/or myomatous nodules of each case for this study Vascular changes in the myomatous endo-and myometrium were characterized by fibrous thickening of the intima, increase of collagens and elastic βbers in the media , splitting and disruption of the internal elatic lamina and hyaline degeneration in the small arteries and arterials proximal to the endometrium. Severity of uterine vascular changes in myometrium were more prominent than those in endometrium and/or myomatous nodules. Out of 30 myomatous uteri studied, 21 cases (7096) revealed hyaline degencration of small arteries and arteries. Encountered in large arteries of myometrium, howeer, were neither finding of the hyaline degeneral ion. It was probably atributcd to the vascular fragility that might underlie the uterine bleeding as a common feature of myomataus uteri. The morphological changes of the blood 、esscls were multifariously modified by aging and pregnancy, but in this study, it seems to be an apparent age related alteration in the blood vessels and the vascular changes were more marked in the multiparous uteri as an effect of gestation and parturition may add to the age related changes that preeede In additions, authors observed the specific feature of pericapi l1ary hyperplasia and sclerosis of collagens and/or fibers in endometrium, which were so called menstrual sclerosis" in the la te secretory phase and gestat ion seierαsis" in the pregnant