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사람태아의 골수외 조혈에 대한 형태학적 관찰 : Morphological observation on the extramedullary hematopoiesis of human fetuses
DC Field | Value | Language |
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dc.contributor.author | 서창인 | - |
dc.contributor.author | 지제근 | - |
dc.date.accessioned | 2009-09-16T10:26:44Z | - |
dc.date.available | 2009-09-16T10:26:44Z | - |
dc.date.issued | 1984-06 | - |
dc.identifier.citation | Seoul J Med, Vol.25 No.2, pp. 117-126 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/9555 | - |
dc.description.abstract | To investigate the extent and temporal regression
of extramedullary hemopoiesis during fetal life , morphological observations on fetal liver , spleen, and thymus were made Normal human embryos and fetuses were collected and proved to be normal after autopsy. The embryos were serially sectioned. Their age ranged from 4 weeks to 42 weeks of gestations. To compare the findings in postnatal life 6 cases of normal newborn infants were also studied In early embryos only primitive red cells originated from extraembryonic source could be seen , but on the 36th day of gestation definitive red cell could first be seen. The liver appeared to be the major organ of hematopoietic activty from late embryo through midfetal period. In the 36th day embryo, macrophages and erythroblast series started to appear and hematopoiesis reached full level of activity from the 11th to 20th week. Thereafter the hematopoiesis decreased gradually to disappear completely by the time of birth. In the liver the most hematopoietic cell were erythroblastic series and the liver was the major source of hematopoiesis during fetal period. And it was thought to be responsible for the fact that the relativc weight of liver of fetus was greater than that of adult. In spleen hematopoietic activity appeared first in the 12th week of gestation. However, the degree of erythropoiesis was minimal in the spleen, and the lymphopoiesis was significantly greater than erythropoietic activity. Therefore it seemed that the spleen plays a minor role in hematopoiesis during fetal period. In thymus lymphocyte appeared first in the 10th week of gestation. Both erythropoiesis and graulocytopoiesis were present in the interlobular septa of the thymus. However, thedegree of hematopoiesis in general was rather smal l. Intramedullary hematopoies began first in the elaviele at the 11th week of gestation | - |
dc.language.iso | ko | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | 사람태아의 골수외 조혈에 대한 형태학적 관찰 | - |
dc.title.alternative | Morphological observation on the extramedullary hematopoiesis of human fetuses | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | Suh, Chang In | - |
dc.contributor.AlternativeAuthor | Chi, Je G. | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 126 | - |
dc.citation.number | 2 | - |
dc.citation.pages | 117-126 | - |
dc.citation.startpage | 117 | - |
dc.citation.volume | 25 | - |
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