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뇌동맥류 수술시 Sodium Nitroprusside 정주효과에 관한 임상적 연구 : Clinical Study on the Effects of Sodium Nitroprusside during Operation of Cerebral Aneurysm
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- Authors
- Issue Date
- 1984-06
- Publisher
- 서울대학교 의과대학
- Citation
- Seoul J Med, Vol.25 No.2, pp. 230-235
- Abstract
- The effect of sodium nitroprusside(SNP) on arterial
blood gas analysis was studied in 15 patients of
intracerebral aneurysm with normal cardio'pulmonary
function under general anesthesia. Systolic arterial
pressure decreased (p<0.005) from I04±1O torr to
85±6 torr, wbereas heart rate increased from 80±12
beats/min. to 92±12 beats/min. Thirty minutes after
discontinuation of SNP, arterial pressure and heart
beat returned to 108±14 torr and 75±8 beats/min. ,
respectively which were the level of pre·administ·
ration of SNP. Arterial pH, PaCO,. PaO, and bicar'
bonate were 7. 41±0.10, 32±6 mmHg, 193±42 mmHg
and 21±1 mEq/1 before'administration of SNP, 7.41
±O.ll, 34±7 mmHg, 188±44 mmHg and 21±2
mEq/1 during administration of SNP, and 7.39±
0.09 , 33±6 mmHg, 193±57 mmHg and 20±3 mEq/
I in 30 minutes after dscontinuation of SNP. There
was no change of pH, PaCO" PaO, and bicarbonate
in levels of pre'administration, during administration
and after discontinuation of SNP.
- ISSN
- 0582-6802
- Language
- Korean
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