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The diagnostic value of multiplanar reconstruction on MDCT colonography for the preoperative staging of colorectal cancer

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dc.contributor.authorJin, Kwang Nam-
dc.contributor.authorLee, Jeong Min-
dc.contributor.authorKim, Se Hyung-
dc.contributor.authorShin, Kyung-Sook-
dc.contributor.authorLee, Jae Young-
dc.contributor.authorHan, Joon Koo-
dc.contributor.authorChoi, Byung Ihn-
dc.date.accessioned2009-09-29T12:24:24Z-
dc.date.available2009-09-29T12:24:24Z-
dc.date.issued2006-06-02-
dc.identifier.citationEur Radiol 16:2284-2291en
dc.identifier.issn0938-7994 (print)-
dc.identifier.issn1432-1084 (online)-
dc.identifier.urihttps://hdl.handle.net/10371/9987-
dc.description.abstractThe purpose of this study was to determine whether multiplanar reconstruction (MPR) images can improve the accuracy of MDCT-based colorectal cancer preoperative staging by receiver-operating characteristic (ROC) analysis. Fifty-five patients with colorectal cancer underwent contrast-enhanced CT colonography using an 8- or 16-row scanner. Two separate interval reviews of the axial MDCT datasets with/without MPR images (coronal and sagittal) were performed independently by two radiologists blinded to both the colonoscopic and histopathologic results. At each review session, the radiologists were asked to determine the colorectal cancer TNM stage within the context of differentiating < or =T3 from T4, N0 from > or =N1 and M0 from M1 using a five-point confidence scale. The radiologists' performance for staging the colorectal cancer using axial CT datasets with/without MPR images was evaluated using ROC analysis. Sensitivities, specificities and interobserver agreement were assessed. When MPR images were added, significant improvement was achieved by both radiologists for differentiating N0 from > or =N1 in terms of both A(Z) (0.651 to 0.769; 0.573 to 0.713) and specificity (26.7 to 69.2%; 23.1 to 76.9%) (P<0.05). For T staging, ROC analysis failed to show a significant improvement in terms of differentiating < or =T3 from T4 for either radiologist (P>0.05), but a significant improvement in the specificity (70 to 90%; 80 to 92%) was achieved by one radiologist (P<0.05). In terms of the M staging, a significant improvement in the Az (0.844 to 0.996) was observed for the combined interpretation of the axial and MPR images by one radiologist (P<0.05). Furthermore, substantial or almost perfect interobserver agreement was achieved for all TNM stagings for the combined interpretations (kappa=0.641-0.866), whereas only fair to substantial agreement was achieved for the axial images alone (kappa=0.337-0.707). In conclusion, the combined interpretation of the axial and MPR MDCT images significantly improved the local staging of colorectal cancer compared with assessments based on axial images alone.en
dc.language.isoenen
dc.publisherSpringer Verlagen
dc.subjectColorectal canceren
dc.subjectPreoperative stagingen
dc.subjectCT colonographyen
dc.subjectMultiplanar reconstructionen
dc.titleThe diagnostic value of multiplanar reconstruction on MDCT colonography for the preoperative staging of colorectal canceren
dc.typeArticleen
dc.contributor.AlternativeAuthor진광남-
dc.contributor.AlternativeAuthor이정민-
dc.contributor.AlternativeAuthor김세형-
dc.contributor.AlternativeAuthor신경숙-
dc.contributor.AlternativeAuthor이재영-
dc.contributor.AlternativeAuthor한준구-
dc.contributor.AlternativeAuthor최병인-
dc.identifier.doi10.1007/s00330-006-0316-0-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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