Browse

Usefulness of 64-slice multidetector computed tomography as an initial diagnostic approach in patients with acute chest pain

Cited 44 time in Web of Science Cited 52 time in Scopus
Authors
Chang, Sung-A; Choi, Sang Il; Choi, Eue-Keun; Kim, Hyung-Kwan; Jung, Jin-Wook; Chun, Eun Ju; Kim, Kyu-Seok; Cho, Young-Seok; Chung, Woo-Young; Youn, Tae-Jin; Chae, In-Ho; Choi, Dong-Ju; Chang, Hyuk-Jae
Issue Date
2008-07-29
Publisher
Elsevier
Citation
Am Heart J. 2008 Aug;156(2):375-83. Epub 2008 May 14.
Keywords
Acute Coronary Syndrome/diagnosis/*radiographyChest Pain/*etiologyCoronary Stenosis/radiographyEmergency Service, HospitalFemaleHospitalization/statistics & numerical dataHumansLength of StayMaleMiddle AgedProspective StudiesTomography, X-Ray Computed/*methods
Abstract
BACKGROUND: Recently, multidetector computed tomography (MDCT) has been proposed as an accurate diagnostic tool to evaluate for coronary artery disease. However, the role of MDCT as part of the initial diagnostic for evaluating acute chest pain is less well established. METHODS: We prospectively enrolled patients presenting with acute chest pain to the emergency department (ED) and risk stratified them based on the pretest probability for an acute coronary syndrome (ACS): (1) very low, (2) low, (3) intermediate, (4) high, and (5) very high or definite. After exclusion of very low and very high risk patients, 268 patients were randomized to either immediate 64-slice cardiac MDCT or a conventional diagnostic strategy. Number of admissions, ED and hospital length of stay (LOS), and major adverse cardiac events over 30 days of follow-up were compared between the strategies based on the pretest probability for ACS. RESULTS: The number of patients ultimately diagnosed with an ACS did not differ between the 2 strategies. Emergency department LOS and total admissions were not different between strategies. Patients in the MDCT-based strategy had a decreased hospital LOS (P = .049) and fewer admissions deemed unnecessary (P = .007). Reductions in unnecessary admissions were more prominent in intermediate-risk patients (P = .015). None of the patients discharged from the ED in the MDCT-based strategy experienced major adverse cardiac events at follow-up. CONCLUSION: Use of an MDCT-based strategy in the ED as part of the initial diagnostic approach for patients presenting with acute chest pain is safe and efficiently reduces avoidable admissions in patients with an intermediate pretest probability for ACS.
ISSN
1097-6744 (Electronic)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18657674

http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6W9H-4SH7F06-3-9&_cdi=6683&_user=168665&_orig=search&_coverDate=08%2F31%2F2008&_sk=998439997&view=c&wchp=dGLbVlW-zSkWb&md5=eb82b6f91336457a880b27421770f65d&ie=/sdarticle.pdf

http://hdl.handle.net/10371/46293
DOI
https://doi.org/10.1016/j.ahj.2008.03.016
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse