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Numerical Changes of Immunoglobulin Containing Cells in the Lymph Nodes Draining the Uterus of Pregnant Mice
임신한 생쥐의 자궁유출 임파절에서 면역 글로불린 함유세포 수의 변화

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Authors
Hwang, Douk Ho; Lee, Kwang Ho; Chang, Ka Young; Baik, Sang Ho; Seoung, Key June; Lee, Byung Lan
Issue Date
1986-09
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med, Vol.27 No.3, pp. 201-209
Keywords
PregnancyImmunoglobulinsLymph nodesImmunohistochemistry
Abstract
This experiment was performed to detect which IgG subclasses are stimulated
by the fetal antigens. The experimental animals were mated syngeneically (female ICR X
male ICR) or allogeneically (female ICR X male DDY), and the renal and lumbar lymph
nodes draining the uterus were dissected out on the 9th and 18th days of pregnancy. The
lymph nodes were stained with methyl green pyronin(MGP) and treated with a immunohistochemical
reaction. Then each group was compared with the virgin control group.
The following results were obtained:
1. In the group of full term mice which were mated syngeneically, the numbers of the
IgG1, IgG2b and IgM containing cells were significantly greater than those of virgin,
2. In the group of mid term mice which were mated allogeneically, the number of the
IgG2b containing cells was significantly greater than that of virgin.
3. In the group of full term mice which were mated allogeneically, the numbers of the
IgGl, IgG2b, IgG3 and IgM containing cells were significantly greater than those of virgin.
4. In the group of full term mice which were mated allogenecially, the numbers of the
IgGl, IgG2b and IgG3 containing cells were significantly greater than those of syngeneic
mating.
On the basis of the above results, it is suggested that the IgG1, IgG2b and IgG3 were
stimulated during pregnancy in mice.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/5510
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 27 No.3 (1986)
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