만성 일산화탄소중독이 백서의 임신손모에 미치는 영향에 관한 실험적 연구

Abstract

An experimental study was performed to observe the effects of chronic carbon monoxide poisoning on the pregnancy wastage of rats. Carbon monoxide poisoning is one of the most serious medical problems in Korea because of the use of anthracite coal briqette as the main domestic fuel. The experimental groups. which were consisted of 51 p~egnant rats. were divided into 3 groups. those are control, experimental group I and experimental group 11. The experimental animals of group I were exposed to 600 ppm of carbon monoxide and those of group II were exposed to 1. 000 ppm of carbon monoxide for 60 minutes daily throughout the full gestational period. The findings and results obtained on the pregnancy wastage. litter size and body weight. body weight of litter by gestational period and hemoglobin value of the rats are summarized as follows: 1. By chronic carbon monoxide poisoning, increased pregnancy wastage. such as early abortion or stillbirth was observed. 2. Decreased body weight of the litters was observed in experimental groups. 3. The body weight of litters by gestational period was also reduced in experimental groups. 4. Hemoglobin value of the rats was moderately increased in experimental groups.